Results 41 to 50 of about 3,154,582 (307)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Structural, electronic, mechanical, optical and magnetic properties of RhNbZ (Z = Li, Si, As) Half-Heusler compounds: a first-principles study

Materials Research Express
Structural, mechanical, electronic, optical and magnetic properties of the cubic RhNbZ (Z = Li, Si, As) half-Heusler compounds is reported using density functional theory (DFT) as implemented in quantum espresso simulation package.
Adem Beriso Bejo, Megersa Wodajo Shura, Kumneger Tadele, Mesfin Asfaw Afrassa, Fekadu Tolessa Maremi   +4 more
doaj   +1 more source

Two binuclear cyanide-bridged Cr(III)-Mn(III) complexes based-on [Cr(2,2’-bipy)(CN)4]- building block: synthesis, crystal structures and magnetic properties

Acta Chimica Slovenica, 2015
Tetracyanide building block [Cr(2,2’-bipy)(CN)4]- and two bicompartimental Schiff-base based manganese(III) compounds have been employed to assemble cyanide-bridged heterometallic complexes, resulting in two cyanide-bridged CrIII-MnIII complexes: [Mn(L1)(
Daopeng Zhang, Lingqian Kong, Hongyan Zhang   +2 more
doaj   +1 more source

Magnetic Properties Regulation of FeGa and FeGaNi Films with Oblique Magnetron Sputtering

Magnetochemistry, 2022
Magnetic FeGa and FeGaNi films with an in-plane anisotropy were deposited by employing oblique magnetron sputtering. With the increase in oblique angle, the crystallite size of FeGa decreases, which indicates that oblique sputtering can refine the ...
Chun Wang, Sanmin Ke, Zhen Wang
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Barium hexaferrite/muscovite heteroepitaxy with mechanically robust perpendicular magnetic anisotropy

npj Flexible Electronics, 2021
Recent advances in the design and development of magnetic storage devices have led to an enormous interest in materials with perpendicular magnetic anisotropy (PMA) property.
Wei-En Ke, Pao-Wen Shao, Chang-Yang Kuo, Haili Song, Rong Huang, Naoki Yagi, Tsuyoshi Kimura, Yugandhar Bitla, Chun-Fu Chang, Ying-Hao Chu   +9 more
doaj   +1 more source

Magnetic property of potassium clusters in pressure-doped zeolite A

, 2007
The pressure-doping technique was developed for further loading of guest potassium metal into porous crystals of zeolite beyond the upper limit at ambient pressure.
N., Nam, Nguyenhoang, H., Shiraga, Hiroyuki, S., Araki, Shingo, Y., Nozue, Yasuo, S., Kawasaki, Shinji   +4 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source