Results 101 to 110 of about 2,555,643 (332)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

open access: yesAdvanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han   +6 more
wiley   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou   +8 more
wiley   +1 more source

Microwave Ultrafast Heating on Iron‐based Nanogap Catalysts for CO2 Reduction Coupling with Coke Removal

open access: yesAdvanced Science, EarlyView.
This study employs a nanogap‐induced microwave discharge strategy to pretreat coke deposits on iron‐based catalysts with engineered nanogaps, causing ultrarapid heating to 1990 K within seconds, selectively eliminating >70% surface carbon deposits and converting waste plastics and greenhouse gases into syngas.
Xi Shen   +4 more
wiley   +1 more source

Influence of Operating Frequency and Ambient Temperature on Reciprocating Magnetic Cooling

open access: yesZhileng xuebao, 2017
To analyze the influence of different working frequencies and room temperatures on the cooling span of a reciprocating room-temperature magnetic refrigeration system, a setup for such a system was designed with granular Gd (particle size: 0.3-0.5 mm) as ...
Wang Qi, Liu Bin, Chen Aiqiang, Li Peng
doaj  

Estimation of Curie temperature of manganite-based materials for magnetic refrigeration application using hybrid gravitational based support vector regression

open access: yesAIP Advances, 2016
Magnetic refrigeration (MR) technology stands a good chance of replacing the conventional gas compression system (CGCS) of refrigeration due to its unique features such as high efficiency, low cost as well as being environmental friendly.
Taoreed O. Owolabi   +4 more
doaj   +1 more source

Investigation on a complex type of magnetic refrigerants for the Ericsson magnetic refrigeration.

open access: yesTEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan), 1986
A complex type of magnetic refrigerant for the Ericsson cycle has been investigated. For the magnetic refrigerant in the temperature range above -15K we have to use the ferromagnetic material, which has the internal magnetic field to arrange its spin system as far as using a magnetic field of -6T, because of increasing of the thermal excitation energy ...
Takasu HASHIMOTO   +5 more
openaire   +2 more sources

Indications of superconductivity in doped highly oriented pyrolytic graphite

open access: yes, 2014
We have observed possible superconductivity using standard resistance vs. temperature techniques in phosphorous ion implanted Highly Oriented Pyrolytic Graphite.
Dresselhaus M S   +4 more
core   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

open access: yesAdvanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang   +11 more
wiley   +1 more source

An All‐Soft Wearable Electrochemiluminescence Chip for Sweat Metabolite Detection

open access: yesAdvanced Science, EarlyView.
A wearable electrochemiluminescence chip for sweat metabolite monitoring is pioneered, integrating “all‐soft” components: a flexible closed bipolar electrode (c‐BPE) array based on laser‐induced graphene (LIG), a laser‐cut microfluidic layer for sweat collection, and deep eutectic solvents (DES)‐based conductive ionogels for ECL emission.
Wei Nie   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy