Results 61 to 70 of about 6,560,420 (350)

SCMR Position Paper (2020) on clinical indications for cardiovascular magnetic resonance

open access: yesJournal of Cardiovascular Magnetic Resonance, 2020
The Society for Cardiovascular Magnetic Resonance (SCMR) last published its comprehensive expert panel report of clinical indications for CMR in 2004.
T. Leiner   +8 more
semanticscholar   +1 more source

Repeatability of Magnetic Resonance Fingerprinting using ISMRM/NIST MRI Phantom in Philips 3T MRI Scanner

open access: yes, 2020
The purpose of this study is to assess the repeatability of the magnetic resonance fingerprinting (MRF) sequence in a Philips 3T scanner with reference to the ISMRM/NIST MRI system phantom.
Au, HT   +5 more
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Design and Implementation of NMR Permanent Magnet Precision Temperature Controller

open access: yesChinese Journal of Magnetic Resonance, 2018
Neodymium-iron-boron (NdFeB) permanent magnets always used to generate a static magnetic field in low field NMR spectrometers has poor temperature stability. Temperature fluctuations will affect the reliability of NMR experiments. In order to improve the
YANG Chang   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Diffusion and utilization of magnetic resonance imaging in Asia. [PDF]

open access: yes, 2002
OBJECTIVES: An assessment of the current status of magnetic resonance imaging (MRI) was undertaken to provide input for future government decisions on the introduction of new technologies in Asia. The objective of the study is to describe and explain the
Hutubessy, Raymond CW   +3 more
core   +4 more sources

Structural Basis for the Inhibition of the Autophosphorylation Activity of HK853 by Luteolin

open access: yesMolecules, 2019
The two-component system (TCS) is a significant signal transduction system for bacteria to adapt to complicated and variable environments, and thus has recently been regarded as a novel target for developing antibacterial agents.
Yuan Zhou   +8 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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