Results 141 to 150 of about 3,716 (206)
Abstract Background The cerebellum has traditionally been regarded as a structure primarily involved in motor coordination. However, accumulating evidence indicates that the cerebellum can exert substantial influence on cognitive and emotional processes.
Daisuke Yoshioka +2 more
wiley +1 more source
Abstract Since 1858, human atherosclerotic plaques have been shown to contain immune cells. But are these cells suitable therapeutic targets? Dozens of clinical trials of anti‐inflammatory agents other than colchicine have been performed in patients with clinically evident atherosclerosis.
Kevin Jon Williams
wiley +1 more source
Abstract Background Pulmonary function tests (PFTs), particularly spirometry, are the reference standard for assessing airflow limitation in respiratory diseases such as chronic obstructive pulmonary disease (COPD) and interstitial pulmonary disease.
Takehiro Shiinoki +5 more
wiley +1 more source
K‐Edge imaging using a clinical dual‐source photon‐counting CT system
Abstract Background Photon‐counting CT (PCCT) enables K‐edge imaging, an advanced multi‐material decomposition technique that requires multiple energy bins to perform decomposition unconstrained by physical assumptions. The clinical implementation of K‐edge imaging applications like dual‐contrast imaging could lead to reductions in radiation dose and ...
Martin V. Rybertt +8 more
wiley +1 more source
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin +40 more
wiley +1 more source
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song +8 more
wiley +1 more source
Abstract BACKGROUND Vascular and glymphatic dysfunction are increasingly implicated in Alzheimer's disease (AD), particularly among apolipoprotein E (APOE) ε4 carriers. We investigated relationships among retinal microvasculature, glymphatic markers, and AD pathology.
William Robert Kwapong +9 more
wiley +1 more source
This study assessed the prognostic value of optical coherence tomography‐derived thicknesses of the peripapillary retinal nerve fiber and ganglion cell‐inner plexiform layer for identifying people with relapsing‐remitting multiple sclerosis at risk of progression independent of relapse activity (PIRA) from two German centers.
Andre Braginets +12 more
wiley +1 more source
Our systematic review and meta‐analysis evaluate whether intravenous thrombolysis (IVT) plus endovascular therapy (EVT) outperforms EVT alone in patients with acute ischemic stroke due to tandem lesions. Pooled data from nine studies involving 1756 patients demonstrate that IVT + EVT is associated with significantly higher rates of functional ...
Wenqian Wei +8 more
wiley +1 more source
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn +10 more
wiley +1 more source

