Results 281 to 290 of about 248,299 (313)
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Molecular Imaging of Atherosclerosis with Magnetic Resonance
2007Despite important clinical advances in the prevention and treatment of atherosclerosis during the past 20 years, atherosclerotic disease remains the first cause of mortality in industrialized countries. 1,2 Atherosclerosis is a complex disease where cholesterol deposition, inflammation, and plaque formation play a major role.
Briley-Saboe, Karen C. +8 more
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Molecular and magnetic resonance imaging: The value of immunoliposomes
Advanced Drug Delivery Reviews, 2009Molecular imaging has the potential to transform the field of diagnostic imaging through enabling far more detailed investigation and characterisation of disease processes than is currently possible. Magnetic resonance imaging (MRI) is capable of three-dimensional non-invasive imaging of opaque tissues at near cellular resolution.
Dorota, Kozlowska +5 more
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Combined magnetic resonance imaging and spectroscopic imaging approach to molecular imaging of prostate cancer [PDF]
Journal of Magnetic Resonance Imaging, 2002 AbstractMagnetic resonance spectroscopic imaging (MRSI) provides a noninvasive method of detecting small molecular markers (historically the metabolites choline and citrate) within the cytosol and extracellular spaces of the prostate, and is performed in conjunction with high‐resolution anatomic imaging.
John Kurhanewicz
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Phosphatidylserine-Targeted Molecular Imaging of Tumor Vasculature by Magnetic Resonance Imaging
Journal of Biomedical Nanotechnology, 2014Phosphatidylserine (PS), normally restricted to the inner leaflet of the plasma membrane, becomes exposed on the outer surface of viable endothelial cells in tumor vasculature, but not in normal blood vessels. In the present study, we report the use of PGN635, a novel human monoclonal antibody that specifically targets PS, for in vivo molecular MRI of ...
Heling, Zhou +8 more
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Magnetic resonance imaging and spectroscopy methods for molecular imaging.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2010Magnetic resonance imaging (MRI), one of the most powerful imaging modalities available for clinical diagnosis, has contributed significantly to phenotyping of transgenic organisms and to cellular imaging and is now gaining importance in the field of molecular imaging. Its advantage is the ability to provide in vivo information with high resolution and
Dresselaers, T. +3 more
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Magnetic resonance imaging of atherosclerosis: classical and molecular imaging
2004Despite advances in both treatment and prevention, complications of atherosclerotic disease remain the leading cause of morbidity and mortality in the Western World. While atherosclerosis may slowly progress over years or decades, the occurrence of thrombosis as a consequence of sudden plaque rupture often leads to abrupt life threatening complications.
René M. Botnar +7 more
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Magnetic resonance nanoparticles for cardiovascular molecular imaging and therapy
Expert Review of Cardiovascular Therapy, 2005Molecular vascular imaging represents a novel tool that promises to change the current medical paradigm of 'see and treat' to a 'detect and prevent' strategy. Nanoparticle agents, such as superparamagnetic nanoparticles and perfluorocarbon nanoparticle emulsions, have been developed for noninvasive imaging, particularly for magnetic resonance imaging ...
Tillmann, Cyrus +4 more
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Molecular aspects of magnetic resonance imaging and spectroscopy
Molecular Aspects of Medicine, 1999Magnetic resonance imaging (MRI) is a well known diagnostic tool in radiology that produces unsurpassed images of the human body, in particular of soft tissue. However, the medical community is often not aware that MRI is an important yet limited segment of magnetic resonance (MR) or nuclear magnetic resonance (NMR) as this method is called in basic ...
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Molecular Imaging and Magnetic Resonance Imaging in Early Diagnosis of Alzheimer's Disease
The Neuroradiology Journal, 2008Alzheimer's disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in the elderly. Magnetic resonance (MR) or computed tomography (CT) imaging is recommended for routine evaluation of dementias. The development of molecular imaging agents and the new techniques of MR for AD are critically important for early ...
SCHILLACI, ORAZIO +8 more
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Magnetic Resonance Molecular Imaging Contrast Agents and Their Application in Atherosclerosis
Topics in Magnetic Resonance Imaging, 2007Heart disease is the most prevalent cause of mortality in the Western world and is most frequently caused by rupture of lesions in the arteries, which are formed by atherosclerosis. Atherosclerosis is a progressive disease, and therefore, there is a strong motivation to be able to image the stages of this disease in vivo.
Mulder, Willem J. M. +5 more
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