Results 41 to 50 of about 14,406 (202)

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

Epilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras, Birgit Frauscher, Jean Gotman, Julia Jacobs, Philippe Kahane, Richard J. Staba, Maeike Zijlmans   +6 more
wiley   +1 more source

Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) and insights into the role of invasive monitoring

Epilepsia, EarlyView.
Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury, Ingmar Blümcke, Robyn M. Busch, Balu Krishnan, Juan Bulacio, William Bingaman, Demitre Serletis, Imad Najm   +7 more
wiley   +1 more source

Unstable slow oscillations couple with epileptogenic fast‐rhythm bistability in sleep‐related epilepsy: A stereoelectroencephalographic study

Epilepsia, EarlyView.
We examined the functional relationship between large‐scale δ‐band phase synchrony and local epileptogenic β–γ‐band amplitude bistability during NREM sleep. Increased synchrony and strong bistability characterized the epileptogenic zone, with strongest effects during N2 sleep, when seizures most frequently occur.
Gaia Burlando, Chiara Belforte, Felix Siebenhühner, Luca Di Tullio, Lorenzo Chiarella, Vladislav Myrov, Frédéric Zubler, Monica Roascio, Francesco Cardinale, Satu Palva, J. Matias Palva, Laura Tassi, Lino Nobili, Gabriele Arnulfo, Sheng H. Wang   +14 more
wiley   +1 more source

Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers, Jawata Afnan, Christoph Braun, Christophe Grova, Dirk‐Matthias Altenmüller, Bernhard J. Steinhoff, Matthias Dümpelmann, Theo Demerath, Horst Urbach, Silke Ethofer, Markus Siegel, Andreas Schulze‐Bonhage, Holger Lerche, Yiwen Li Hegner   +13 more
wiley   +1 more source

Frequency-Resolved Cortical Functional Connectivity Across the Adult Lifespan. [PDF]

Hum Brain Mapp
An analysis of magnetoencephalography (MEG) recordings from 576 adults aged 18–87 years revealed frequency‐dependent changes in cortical functional connectivity across the adult lifespan, which are not explained by changes in source power. Beta‐band (13–30 Hz) connectivity at rest is associated with sensorimotor attenuation independent of these age ...
Ruuskanen S, Avendano-Diaz JC, Liljeström M, Parkkonen L.   +3 more
europepmc   +2 more sources

Thalamic connectivity mirrors spatial maps of network dysfunction in nonlesional focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Focal epilepsy is increasingly conceptualized as a network disorder, yet the extent to which network dysfunction reflects a shared phenotype remains unknown. Spatially conserved patterns of network dysfunction may implicate a centralized mechanism underlying widespread impairment.
Joline M. Fan, Ehsan Tadayon, Kiwamu Kudo, Kamalini G. Ranasinghe, Anne M. Findlay, Robert C. Knowlton, Vikram R. Rao, Srikantan S. Nagarajan   +7 more
wiley   +1 more source

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Journal of Integrative Neuroscience
Background: Magnetoencephalography (MEG) is a non-invasive imaging technique for directly measuring the external magnetic field generated from synchronously activated pyramidal neurons in the brain.
Xin Zhang, Yan Chang, Hui Wang, Yin Zhang, Tao Hu, Xiao-yu Feng, Ming-kang Zhang, Ze-kun Yao, Chun-qiao Chen, Jia-yu Xu, Fang-yue Fu, Qing-qian Guo, Jian-bing Zhu, Hai-qun Xie, Xiao-dong Yang   +14 more
doaj   +1 more source

Non-Invasive Functional-Brain-Imaging with an OPM-based Magnetoencephalography System.

PLoS ONE, 2020
A non-invasive functional-brain-imaging system based on optically-pumped-magnetometers (OPM) is presented. The OPM-based magnetoencephalography (MEG) system features 20 OPM channels conforming to the subject's scalp. We have conducted two MEG experiments
Amir Borna, Tony R Carter, Anthony P Colombo, Yuan-Yu Jau, Jim McKay, Michael Weisend, Samu Taulu, Julia M Stephen, Peter D D Schwindt   +8 more
doaj   +1 more source

A comparison of minimum norm and MUSIC for a combined MEG/EEG sensor array [PDF]

Advances in Radio Science, 2012
Many different algorithms for imaging neuronal activity with magnetoencephalography (MEG) or electroencephalography (EEG) have been developed so far. We validate the result of other authors that a combined MEG/EEG sensor array provides smaller source ...
H. Ahrens, F. Argin, L. Klinkenbusch
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source