Background. Current methods of targeted cancer therapy are not always effective enough and can lead to side effects, such as an increased risk of autoimmune diseases.
Svitlana Gorobets +2 more
doaj +1 more source
Semicontinuous culture of Magnetospirillum gryphiswaldense MSR-1 cells in an autofermentor by nutrient-balanced and isosmotic feeding strategies. [PDF]
ABSTRACT An improved strategy was developed for the high-density culture of Magnetospirillum gryphiswaldense strain MSR-1 and large-scale magnetosome production in both 7.5- and 42-liter autofermentors.
Zhang Y, Zhang X, Jiang W, Li Y, Li J.
europepmc +4 more sources
A Novel Highly Efficient Device for Growing Micro-Aerophilic Microorganisms
This work describes a novel, simple and cost-effective culture system, named the Micro-Oxygenated Culture Device (MOCD), designed to grow microorganisms under particularly challenging oxygenation conditions.
Maxime Fuduche +4 more
doaj +1 more source
Development of a simple intensified fermentation strategy for growth of Magnetospirillum gryphiswaldense MSR-1: Physiological responses to changing environmental conditions. [PDF]
The development of a simple pH-stat fed-batch fermentation strategy for the production of Magnetospirillum gryphiswaldense MSR-1 and magnetosomes (nanoscale magnetic organelles with biotechnological applications) is described. Flow cytometry was exploited as a powerful analytical tool for process development, enabling rapid monitoring of cell ...
Fernández-Castané A +3 more
europepmc +3 more sources
Two bifunctional enzymes with ferric reduction ability play complementary roles during magnetosome synthesis in Magnetospirillum gryphiswaldense MSR-1. [PDF]
The bacterial strain Magnetospirillum gryphiswaldense MSR-1 does not produce siderophores, but it absorbs a large amount of ferric iron and synthesizes magnetosomes. We demonstrated previously the presence of six types of ferric reductase isozymes (termed FeR1 through FeR6) in MSR-1.
Zhang C +7 more
europepmc +4 more sources
Magnetizing Biotech-Advances in (In Vivo) Magnetic Enzyme Immobilization. [PDF]
ABSTRACT Industrial biocatalysis, a multibillion dollar industry, relies on the selectivity and efficacy of enzymes for efficient chemical transformations. However, enzymes, evolutionary adapted to mild biological conditions, often struggle in industrial processes that require harsh reaction conditions, resulting in reduced stability and activity ...
Ölçücü G, Jaeger KE, Krauss U.
europepmc +2 more sources
Different types of biomineralization, including calcification, silicification, iron, carbon, nitrogen, and phosphorus mineralization, which are mediated by algae, bacteria, fungi, and viruses, are summarized. The mechanisms of extracellular and intracellular microbe‐mediated mineralization, as well as their environmental, industrial, and ...
Wen Qin +7 more
wiley +1 more source
Epsilon-Fe2O3 is a novel intermediate for magnetite biosynthesis in magnetotactic bacteria
Background Natural biological magnetite nanoparticles are widely distributed from microorganisms to humans. It is found to be very important in organisms, especially in navigation.
Tong Wen +9 more
doaj +1 more source
Using genetic engineering techniques, a versatile toolkit for the multifunctionalization of bacterial magnetic nanoparticles is developed. High‐level magnetosome display of different cargo proteins enables the generation of magnetic, fluorescent, catalytically active particles that can be efficiently incorporated into a hydrogel‐based matrix, which ...
Frank Mickoleit +2 more
wiley +1 more source
Constraining the magnetic properties of ultrafine- and fine-grained biogenic magnetite
Four samples containing ultrafine- and fine-grained magnetite of magnetoferritins and magnetotactic bacteria cells were magnetically characterized at both room and low temperatures.
Tongwei Zhang, Yongxin Pan
doaj +1 more source

