Results 61 to 70 of about 236,983 (297)
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Magnetic Materials: Novel Monitors of Long-Term Evolution of Engineered Barrier Systems
Most safety cases for the deep geological disposal of radioactive waste are reliant on the swelling of bentonite in the engineered barrier system as it saturates with groundwater.
Simon L. Harley +2 more
doaj +1 more source
Underestimated risks of rare-earth magnet ingestion in children: when does it need surgery? [PDF]
This review discusses an underestimated risk of rare-earth magnet (henceforth, magnet) ingestion in children and its surgical indication. Due to the ubiquity of magnets, the incidence of magnet ingestion has rapidly increased.
So-Hyun Nam
doaj +1 more source
Using LSTM recurrent neural networks for monitoring the LHC superconducting magnets
The superconducting LHC magnets are coupled with an electronic monitoring system which records and analyses voltage time series reflecting their performance.
Mertik, Matej +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Rare earth elements (REEs) are critical to our modern world. Recycling REEs from used products could help with potential supply issues. Extracting REEs from chloride media with tetrabutyl diglycolamide (TBDGA) in carbon dioxide could help recycle REEs ...
Mary Case +3 more
doaj +1 more source
We developed an end-effector-type rehabilitation robot that can uses electro- and permanent magnets to generate a three-way magnetic field to assist hand movements and perform rehabilitation therapy. This study aimed to investigate the therapeutic effect
Sung-Hoon Kim +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Electromagnets for an endoscopic anastomosis tool in the colon
The goal of our research work is the development of a novel endoscopic anastomosis device for the colon. One of the main challenges in this context is the application of forces at the endoscope tip to rejoin the two bowel endings.
Steger Jana +3 more
doaj +1 more source

