Results 61 to 70 of about 55,798 (268)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Investigation of the unusual magnetic properties of Fe and Co on MgO with high spatial, energy and temporal resolution [PDF]

open access: yes, 2015
Nanometer-sized magnets are used as magnetic bits in data storage devices to hold information. As such devices are further miniaturized, the control of magnetism at the atomic scale becomes essential.
Baumann, Susanne
core   +1 more source

Impurity Phases and Hydrogen Decrepitation of Sm2TM17 Sintered Magnet Production Scrap

open access: yesNanomaterials
Sm2TM17 sintered magnets, (where TM = Co, Fe, Cu, Zr), are typically utilised in high temperature magnetic applications due to their magnetic properties being very stable at 200–350 °C.
James Griffiths   +6 more
doaj   +1 more source

Extraction of Rare Earth Elements from Chloride Media with Tetrabutyl Diglycolamide in 1-Octanol Modified Carbon Dioxide

open access: yesMetals, 2019
Rare earth elements (REEs) are critical to our modern world. Recycling REEs from used products could help with potential supply issues. Extracting REEs from chloride media with tetrabutyl diglycolamide (TBDGA) in carbon dioxide could help recycle REEs ...
Mary Case   +3 more
doaj   +1 more source

Three-Dimensional Magnetic Rehabilitation, Robot-Enhanced Hand-Motor Recovery after Subacute Stroke: A Randomized Controlled Trial

open access: yesBrain Sciences, 2023
We developed an end-effector-type rehabilitation robot that can uses electro- and permanent magnets to generate a three-way magnetic field to assist hand movements and perform rehabilitation therapy. This study aimed to investigate the therapeutic effect
Sung-Hoon Kim   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Electromagnets for an endoscopic anastomosis tool in the colon

open access: yesCurrent Directions in Biomedical Engineering, 2021
The goal of our research work is the development of a novel endoscopic anastomosis device for the colon. One of the main challenges in this context is the application of forces at the endoscope tip to rejoin the two bowel endings.
Steger Jana   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Effect of Magnetic Field on Bone Healing around Endosseous Implants – An In-vivo Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: After implant placement, a stress-free healing period of 3-6 months is a pre-requisite to achieve good osseointegration. If this duration could be reduced, the patients would feel happier.
Mahalakshmi Gujjalapudi   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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