Results 111 to 120 of about 896,035 (305)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Magnification and Refocusing Comparison in Cataract Surgery Using a Heads-Up Three-Dimensional Visualization System versus Conventional Binocular Microscopy

open access: yes, 2023
Mariana Ramírez Mejía,1 Leticia Arroyo Muñoz,1 Ana Beatriz Medina Perez,1 Cristina Mendoza Velasquez,1 Jimena Ceja Martínez,1 Azyadeh Camacho Ordonez,1 Oscar Guerrero-Berger1,2 1Department of Anterior Segment Surgery, Fundaci ...
Arroyo Muñoz L   +6 more
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Scabies mite magnification

open access: yes, 1997
The scraping is viewed under the microscope at low magnification. The scabies mite measures about .1 to .3 mm in diameter, and is not visible with the naked eye, but very slight magnification will make it ...
Bezzant, John L.
core  

TEM micrographs: a) glc-IONP (magnification 250000x); b) PVP-IONP (magnification 160000x).

open access: yes, 2015
TEM micrographs: a) glc-IONP (magnification 250000x); b) PVP-IONP (magnification 160000x).
Valentina Gandin (296404)   +8 more
core   +1 more source

Enhanced Approaches to Gravitational Lensing: A Regular Charged Black Hole in Weak Field Limit

open access: yesSpektra: Jurnal Fisika dan Aplikasinya
Gravitational lensing, an integral aspect of general relativity, profoundly impacts our understanding of black holes (BH’s). The presence of a centered singularity resulting from gravitational collapse is a fundamental characteristic of a BH. Nonetheless,
H. M. U. Din, H. S. Ramadhan
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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