Results 121 to 130 of about 166,004,902 (280)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

A completeness analysis of the National Seismic Network of Italy

, 2009
Accepted for publication in Journal of Geophysical Research. Copyright (2009) American Geophysical Union. Further reproduction or electronic distribution is not permitted.We present the first detailed study of earthquake detection capabilities of the ...
Mele, F., Marzocchi, W., Schorlemmer, D.
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Improving the estimation of detection probability and magnitude of completeness in strongly heterogeneous media, an application to acoustic emission (AE)

, 2013
Reliable estimations of magnitude of completeness (M-c) are essential for a correct interpretation of seismic catalogues. The spatial distribution of M-c may be strongly variable and difficult to assess in mining environments, owing to the presence of ...
Hainzl, Sebastian, Dahm, Torsten (Prof.), Becker, Dirk, Maghsoudi, Samira, Kaiser, Diethelm, Cesca, Simone (Dr.)   +5 more
core   +1 more source

Hybrid Forward-Backward Ray Tube Propagation Model for Deterministic Multipath Channel Prediction

Sensors
Deterministic propagation prediction faces a fundamental trade-off: the image method is exact but single-mechanism, while the shooting and bouncing ray method is flexible yet suffers from path omissions due to discrete sampling.
Qi Yao, Zhongyu Liu, Lixin Guo
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

The effect of ocular surface conditions on blink rate and completeness [PDF]

, 2011
A healthy human would be expected to show periodic blinks, making a brief closure of the eyelids. Most blinks are spontaneous, occurring regularly with no external stimulus.
Roshani, Shila
core  

Quantifying the Limits of TESS Stellar Rotation Measurements with the K2-TESS Overlap

The Astrophysical Journal
The Transiting Exoplanet Survey Satellite (TESS) has provided stellar rotation periods across much of the sky through high-precision light curves, but the reliability and completeness of these measurements require careful evaluation.
Andrew W. Boyle, Andrew W. Mann, Jonathan Bush   +2 more
doaj   +1 more source