Results 51 to 60 of about 450,296 (238)

Same-Different Judgments With Alphabetic Characters: The Case of Literal Symbol Processing

open access: yesJournal of Numerical Cognition, 2019
Learning mathematics requires fluency with symbols that convey numerical magnitude. Algebra and higher-level mathematics involve literal symbols, such as "x", that often represent numerical magnitude.
Courtney Pollack
doaj   +1 more source

Dissociable Processes for Orientation Discrimination Learning and Contextual Illusion Magnitude [PDF]

open access: yesPLoS ONE, 2014
Previous research suggests an inverse relationship between human orientation discrimination sensitivity and tilt illusion magnitude. To test whether these perceptual functions are inherently linked, we measured both orientation discrimination sensitivity and the magnitude of the tilt illusion before and after participants had been trained for three ...
Wilks, Charlotte Elizabeth Holmes   +2 more
openaire   +6 more sources

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen   +5 more
wiley   +1 more source

Time and magnitude monitoring based on the renewal reward process

open access: yesReliability Engineering & System Safety, 2018
Time between event (TBE) charts are SPC tools for monitoring the occurrence of unwanted events, such as the appearance of a defective item or a failure of a piece of equipment. In some cases, a magnitude, indicating the severity of the event, is also measured.
Sajid Ali 0001, Antonio Pievatolo
openaire   +2 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effect of numerical magnitude on the perceptual processing speed of a digit

open access: yesJournal of Vision, 2014
In this study, we investigated whether the numerical information of a digit would affect perceptual processing speed for that digit. In Experiment 1, participants performed a temporal order judgment (TOJ) task in which they judged the order of two digits presented briefly to the left or right of the fixation point with a short asynchrony.
Shuang-Xia, Li, Yong-Chun, Cai
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Age does not count: resilience of quantity processing in healthy aging

open access: yesFrontiers in Psychology, 2013
Quantity skills have been extensively studied in terms of their development and pathological decline. Recently, numerosity discrimination has been shown to be remarkably resilient to healthy ageing, but whether processing continuous quantities such as ...
Anna eLambrechts   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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