Results 161 to 170 of about 28,289 (266)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A Note on "A Comparison of Two Methods for Adaptive Multi-Arm Two-Stage Design". [PDF]

Stat Med
Jörgens S, Wassmer G.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Intraspecific variation in animal mating signals: a test of Mayr's conjecture. [PDF]

Behav Ecol
Gray DA.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Disentangling Boltzmann Brains, the Time-Asymmetry of Memory, and the Second Law. [PDF]

Entropy (Basel)
Wolpert D, Rovelli C, Scharnhorst J.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

STARK SYSTEMS AND EQUIVARIANT MAIN CONJECTURES

STARK SYSTEMS AND EQUIVARIANT MAIN CONJECTURES
The theory of Stark systems due to Burns, Sakamoto, and Sano is an important tool toward main conjectures in Iwasawa theory. In this paper, we propose a new perspective of their results, which produces more refined consequences. As a principal application, we prove one divisibility of the equivariant main conjecture for elliptic curves, under certain ...
openaire   +1 more source

Why is it easier to predict the epidemic curve than to reconstruct the underlying contact network? [PDF]

J Math Biol
Keliger D, Horváth I.
europepmc   +1 more source

A NOTE ON THE MAIN CONJECTURE OVER ℚ

A NOTE ON THE MAIN CONJECTURE OVER ℚ
In this note we show how the main conjecture of the Iwasawa theory over ℚ has a natural place in the context of the Galois representation of Gal(ℚ^^ー/ℚ) on the etale pro-p fundamental group of the projective line minus three points. However we still need to assume the Vandiver conjecture to get a proof of the main conjecture in this context.
openaire