FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
QbD-Based Design Space Development for Honey-Containing Traditional Chinese Medicine Tablets Assisted by the SeDeM Expert System and Machine Learning. [PDF]
PharmaceuticsDeng X +5 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Experience of workplace violence among clinical faculty members of Isfahan University of Medical Sciences: A qualitative study. [PDF]
J Educ Health PromotYavari M, Haghani F, Omid A, Malekian A.
europepmc +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Preoperative risk factors and their cumulative impact on nonsatisfaction after benign hysterectomy: A population-based nation-wide register study. [PDF]
Acta Obstet Gynecol ScandMakdessi Björkström L +5 more
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Propagating wellness: understanding the communication mechanisms of yoga and Wuqinxi (five animal frolics) via Lasswell's 5W framework. [PDF]
Front Public HealthSong Y, Lu L, Luo H.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Enhancement Mechanisms of Multi-Scale Huff-and-Puff in Horizontal Wells for Tight Sandstone Reservoirs‑A Case Study of the Chang 6<sub>3</sub> Formation in the Wuqi Block, Ordos Basin. [PDF]
ACS OmegaZhang X, Shi Y, Ma Y, Wang Y, Zhang J.
europepmc +1 more source