Results 91 to 100 of about 4,192,840 (340)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Spectral Variability of Herbig Ae Star V1295, Aquila

Galaxies
This article presents the results of long-term spectral studies of the unusual Herbig Ae star V1295 Aql. The variability in the spectrophotometric parameters of the emission and absorption components of the hydrogen lines Hα, Hβ, and D Na I—and of ...
Hemayil Adigozalzade, Silva Jarvinen, Swetlana Hubrig, Ulviyya Bashirova, Nariman Ismailov   +4 more
doaj   +1 more source

Astrobiological Effects of F, G, K and M Main-Sequence Stars

, 2008
We focus on the astrobiological effects of photospheric radiation produced by main-sequence stars of spectral types F, G, K, and M. The photospheric radiation is represented by using realistic spectra, taking into account millions or hundred of millions ...
E. F. Guinan, Goldsmith, L. Gurdemir, M. Cuntz, R. L. Kurucz   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Planetary Obliquity Excitation through Pre-main-sequence Stellar Evolution

The Astrophysical Journal
A planet’s axial tilt (“obliquity”) substantially affects its atmosphere and habitability. It is thus essential to comprehend the various mechanisms that can excite planetary obliquities, particularly at the primordial stage.
Sidhant Kumar Suar, Sarah C. Millholland
doaj   +1 more source

NGC1818 unveils the origin of the extended main-sequence turn-off in young Magellanic Clouds clusters. [PDF]

Nat Commun, 2022
Cordoni G, Milone AP, Marino AF, Cignoni M, Lagioia EP, Tailo M, Carlos M, Dondoglio E, Jang S, Mohandasan A, Legnardi MV.   +10 more
europepmc   +1 more source

CO Emission, Molecular Gas, and Metallicity in Main-Sequence Star-Forming Galaxies at $z\sim2.3$ [PDF]

, 2022
Ryan L. Sanders, Alice E. Shapley, Tucker Jones, Irene Shivaei, Gergö Popping, Naveen A. Reddy, Romeel Davé, Sedona H. Price, Bahram Mobasher, Mariska Kriek, Alison L. Coil, Brian Siana   +11 more
openalex   +1 more source

Age Constraints for an M31 Globular Cluster from Main Sequence Photometry

, 2004
We present a color-magnitude diagram (CMD) of the globular cluster SKHB-312 in the Andromeda galaxy (M31), obtained with the Advanced Camera for Surveys on the Hubble Space Telescope.
Allen V. Sweigart, Alvio Renzini, Don A. VandenBerg, Ed Smith, Heitsch E., Henry C. Ferguson, R. Michael Rich, Randy A. Kimble, Thomas M. Brown   +8 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The saccade main sequence revised: A fast and repeatable tool for oculomotor analysis. [PDF]

Behav Res Methods, 2021
Gibaldi A, Sabatini SP.
europepmc   +1 more source