Results 111 to 120 of about 3,775,717 (320)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Timescale of Mass Accretion in Pre-Main-Sequence Stars

, 2009
We present initial result of a large spectroscopic survey aimed at measuring the timescale of mass accretion in young, pre-main-sequence stars in the spectral type range K0 - M5.
Allen, Barrado y Navascués, Basri, Beristain, Boss, Boss, Bouwman, Briceño, Briceño, Caballero, Carpenter, Clarke, D. Fedele, Dahm, Damjanov, Flaherty, Forbes, Haisch, Haisch, Hartmann, Hartmann, Herczeg, Hernández, Horne, J. M. Oliveira, Jayawardhana, Jeffries, Kharchenko, Lada, Luhman, M. E. van den Ancker, Mentuch, Mohanty, Moraux, Natta, Oliveira, Oliveira, Park, Pollack, R. Jayawardhana, Sana, Schmidt, Sicilia-Aguilar, Sicilia-Aguilar, Sicilia-Aguilar, Th. Henning, Thommes, White, Wilking, Winston, Zapatero Osorio, Zuckerman   +51 more
core   +1 more source

Binaries Having One Component Below the Main Sequence [PDF]

, 1958
Jorge Sahade
openalex   +1 more source

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

Molecular Oncology, EarlyView.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park, Keeok Haam, Haejeong Heo, Doyeong Kim, Min‐Ju Kim, Hyo‐Jung Jung, Seongwon Cha, Mirang Kim, Haeseung Lee   +8 more
wiley   +1 more source

On the Role of the Guillotine Factor in Determining the Structure of Late Type Main Sequence Stars [PDF]

, 1949
R. Williamson, G. F. D. Duff, C. A. Chant   +2 more
openalex   +1 more source

Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma

Molecular Oncology, EarlyView.
Ewing sarcoma is driven by the EWS::FLI1 fusion protein, which disrupts gene expression by hijacking the BAF complex via ARID1A. ARID1A's ability to form biomolecular condensates is crucial for tumor growth, making it a potential therapeutic target. However, targeting these transient condensates is challenging, requiring further research. Ewing sarcoma,
Erich J. Sohn, David S. Libich
wiley   +1 more source

Collisions and close encounters involving massive main-sequence stars

, 2006
We study close encounters involving massive main sequence stars and the evolution of the exotic products of these encounters as common--envelope systems or possible hypernova progenitors.
Dale, James E., Davies, Melvyn B.
core   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Expansion of Accreting Main-sequence Stars during Rapid Mass Transfer

The Astrophysical Journal Letters
Accreting main-sequence stars expand significantly when the mass accretion timescale is much shorter than their thermal timescales. This occurs during mass transfer from an evolved giant star onto a main-sequence companion in a binary system and is an ...
Mike Y. M. Lau, Ryosuke Hirai, Ilya Mandel, Christopher A. Tout   +3 more
doaj   +1 more source