Results 121 to 130 of about 3,775,717 (320)

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

open access: yesMolecular Oncology, EarlyView.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso   +12 more
wiley   +1 more source

The potential of space observations for pulsating pre-main sequence stars

open access: yesEPJ Web of Conferences, 2017
The first asteroseismic studies of pre-main sequence (pre-MS) pulsators have been conducted based on data from the space telescopes MOST and CoRoT with typical time bases of less than 40 days.
Zwintz Konstanze
doaj   +1 more source

A Test Of Pre-Main-Sequence Lithium Depletion Models [PDF]

open access: yes, 2010
Despite the extensive study of lithium depletion during pre-main-sequence (PMS) contraction, studies of individual stars show discrepancies between ages determined from the Hertzsprung-Russell (H-R) diagram and ages determined from lithium depletion ...
Jensen, Eric L.N.   +1 more
core   +1 more source

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

open access: yesMolecular Oncology, EarlyView.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang   +6 more
wiley   +1 more source

An Episode of Occultation Events in Gaia21bcv

open access: yesThe Astronomical Journal
A previously unremarkable star near the Canis Major OB1/R1 association underwent an episode of multiple deep brightness minima. Light curves based on archival Gaia, Zwicky Transient Facility (ZTF), and NEOWISE data and additional observations from the ...
Klaus W. Hodapp   +6 more
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

The 4–400 GHz Survey for the 32 Class II Disks in the Taurus Molecular Cloud

open access: yesThe Astrophysical Journal Supplement Series
We have compiled the ∼4–400 GHz broad spectra of 32 Class II protoplanetary disks (PPDs) in the Taurus-Auriga region, which represents the brightest one-third of sources detected in the submillimeter band in this region.
Chia-Ying Chung   +6 more
doaj   +1 more source

Mapping the Galactic halo with main-sequence and RR Lyrae stars

open access: yesEPJ Web of Conferences, 2012
We present an analysis of Galactic halo structure, substructure, and metallicity traced by main-sequence and RR Lyrae stars selected from the SDSS stripe 82 and CFHT Legacy Survey data sets.
Sesar B.
doaj   +1 more source

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