Results 131 to 140 of about 3,775,717 (320)

On Stellar Rotation: I. The Rotation of Upper Main-Sequence Stars [PDF]

, 1964
I. W. Roxburgh
openalex   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Molecular Oncology, EarlyView.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto, Hege Marie Vedeld, Guro Elisabeth Lind, Marine Jeanmougin   +3 more
wiley   +1 more source

Constraining Stellar Rotation at the Zero-age Main Sequence with TESS

The Astrophysical Journal
The zero-age main sequence (ZAMS) is a critical phase for stellar angular momentum evolution, as stars transition from contraction-dominated spin-up to magnetic wind-dominated spin-down.
S. T. Douglas, P. A. Cargile, S. P. Matt, A. A. Breimann, J. A. Pérez Chávez, C. X. Huang, N. J. Wright, G. Zhou   +7 more
doaj   +1 more source

A planet within the debris disk around the pre-main-sequence star AU Microscopii. [PDF]

Nature, 2020
Plavchan P, Barclay T, Gagné J, Gao P, Cale B, Matzko W, Dragomir D, Quinn S, Feliz D, Stassun K, Crossfield IJM, Berardo DA, Latham DW, Tieu B, Anglada-Escudé G, Ricker G, Vanderspek R, Seager S, Winn JN, Jenkins JM, Rinehart S, Krishnamurthy A, Dynes S, Doty J, Adams F, Afanasev DA, Beichman C, Bottom M, Bowler BP, Brinkworth C, Brown CJ, Cancino A, Ciardi DR, Clampin M, Clark JT, Collins K, Davison C, Foreman-Mackey D, Furlan E, Gaidos EJ, Geneser C, Giddens F, Gilbert E, Hall R, Hellier C, Henry T, Horner J, Howard AW, Huang C, Huber J, Kane SR, Kenworthy M, Kielkopf J, Kipping D, Klenke C, Kruse E, Latouf N, Lowrance P, Mennesson B, Mengel M, Mills SM, Morton T, Narita N, Newton E, Nishimoto A, Okumura J, Palle E, Pepper J, Quintana EV, Roberge A, Roccatagliata V, Schlieder JE, Tanner A, Teske J, Tinney CG, Vanderburg A, von Braun K, Walp B, Wang J, Wang SX, Weigand D, White R, Wittenmyer RA, Wright DJ, Youngblood A, Zhang H, Zilberman P.   +86 more
europepmc   +1 more source

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, EarlyView.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source

On Stellar Rotation: II. The Rotation of Lower Main Sequence Stars [PDF]

, 1964
I. W. Roxburgh
openalex   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Surface-Gravity Determinations for Main-Sequence B Stars [PDF]

, 1968
S. E. Strom, D. M. Peterson
openalex   +1 more source

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

Molecular Oncology, EarlyView.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits, Barbara Andrea Reinoehl, Renate Wagner, Peter Kuess, Franziska Eckert, Anna Sophie Berghoff, Thorsten Fuereder, Rotraud Wieser   +7 more
wiley   +1 more source