Results 41 to 50 of about 3,873,512 (229)

Nitrogen chronology of massive main sequence stars

, 2012
Rotational mixing in massive main sequence stars is predicted to monotonically increase their surface nitrogen abundance with time. We use this effect to design a method for constraining the age and the inclination angle of massive main sequence stars ...
A. de Koter, Brott, Brott, Buonanno, Charbonnel, de Mink, Dufton, Endal, Evans, Evans, Heger, Hubeny, Hunter, Hunter, Hunter, Hunter, I. Brott, K. Köhler, M. Borzyszkowski, Maeder, Maeder, Meynet, Meynet, Mokiem, N. Langer, Przybilla, Salpeter, Sana, Schaerer, Vink, Vink, Vink   +31 more
core   +2 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Entropy Production of Main-Sequence Stars [PDF]

Entropy, 2015
The entropy production (inside the volume bounded by a photosphere) of main-sequence stars is calculated based on B–V photometry data. The entropy-production distribution function and the dependences of entropy production on temperature and luminosity are obtained for these stars for the first time.
Leonid Martyushev, Sergey Zubarev
openaire   +4 more sources

New evolutionary models for pre-main sequence and main sequence low-mass stars down to the hydrogen-burning limit

, 2015
We present new models for low-mass stars down to the hydrogen-burning limit that consistently couple atmosphere and interior structures, thereby superseding the widely used BCAH98 models.
Allard, F., Baraffe, I., Chabrier, G., Homeier, D.   +3 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

MAIN SEQUENCE EVOLUTION WITH LAYERED SEMICONVECTION [PDF]

The Astrophysical Journal, 2016
ABSTRACT Semiconvection is a form of mixing in thermally unstable regions that are partially stabilized by composition gradients. It has the greatest potential impact on the evolution of the cores of main sequence stars in the mass range –
Kevin Moore, Pascale Garaud
openaire   +3 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

SDSS-IV MANGA: Spatially Resolved Star Formation Main Sequence and LI(N)ER Sequence [PDF]

, 2017
We present our study on the spatially resolved H_alpha and M_star relation for 536 star-forming and 424 quiescent galaxies taken from the MaNGA survey.
Barrera-Ballesteros, J. K., Bizyaev, D., Boquien, M., Brownstein, J., Cano-díaz, M., Cruz-González, I., Hagen, A., Hsieh, B. C., Hsu, C. H., Ibarra, H., Lin, J. H., Lin, Lihwai, Oravetz, D., Pan, H. A., Pan, K., Riffel, R., Simmons, A., Sánchez, S. F., Yan, R., Zhang, K.   +19 more
core   +3 more sources