Results 51 to 60 of about 4,192,840 (340)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Accurate fundamental parameters for Lower Main Sequence Stars

open access: yes, 2006
We derive an empirical effective temperature and bolometric luminosity calibration for G and K dwarfs, by applying our own implementation of the InfraRed Flux Method to multi-band photometry.
C. Flynn   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Chandra Cygnus OB2 Legacy Survey: Design and X-Ray Point-source Catalog

open access: yesThe Astrophysical Journal Supplement Series, 2023
The Cygnus OB2 association is the largest concentration of young and massive stars within 2 kpc of the Sun, including an estimated ∼65 O-type stars and hundreds of OB stars.
Nicholas J. Wright   +7 more
doaj   +1 more source

Atmospheric velocity fields in tepid main sequence stars

open access: yes, 2009
The line profiles of the stars with v sin i below a few km/s can reveal direct signatures of local velocity fields (e.g. convection) in stellar atmospheres. This effect is well established in cool main sequence stars, and has been detected and studied in
A. Townshend   +41 more
core   +2 more sources

Reconciling Mass Functions with the Star-Forming Main Sequence Via Mergers [PDF]

open access: yes, 2017
We combine star formation along the `main sequence', quiescence, and clustering and merging to produce an empirical model for the evolution of individual galaxies.
Capak, Peter   +2 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Common Warm Dust Temperatures Around Main-sequence Stars [PDF]

open access: yes, 2011
We compare the properties of warm dust emission from a sample of main-sequence A-type stars (B8-A7) to those of dust around solar-type stars (F5-K0) with similar Spitzer Space Telescope Infrared Spectrograph/MIPS data and similar ages.
Bryden, G.   +5 more
core   +1 more source

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