Results 61 to 70 of about 3,957,653 (321)

Quasar main sequence: A line or a plane [PDF]

open access: yesAstronomy & Astrophysics, 2019
Context. A quasar main sequence is widely believed to reveal itself through objects represented in a plane spanned by two parameters: the full width at half maximum (FWHM) of Hβ and the ratio of Fe II to Hβ equivalent width. This sequence is related to the application to quasar properties of principal component analysis (PCA), which reveals that the ...
Conor Wildy   +2 more
openaire   +4 more sources

Main trends of the quasar main sequence - effect of viewing angle [PDF]

open access: yesContributions of the Astronomical Observatory Skalnaté Pleso, 2020
We address the effect of the viewing angle of the accretion disk plane and the geometry of the broad-line region (BLR) with the goal of interpreting the distribution of quasars along the main sequence (MS). We utilize photoionization code CLOUDY to model the BLR FeII emission, incorporating the grossly underestimated role of the form factor (f).
Panda, S., MARZIANI, Paola, Czerny, B.
openaire   +4 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

The Enigmatic, Highly Variable, High-Mass Young Stellar Object Mol 12: A New Extreme Herbig Be (Proto)star

open access: yesGalaxies
We report new medium-resolution spectroscopy covering the wavelength range from 0.6 to 2.4 μm, as well as multi-epoch, multi-wavelength photometry, of the Class I high-mass embedded young stellar object Mol 12 (IRAS 05373+2349). It is embedded (AV≃12) in
Mauricio Tapia   +3 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Massive pre-main sequence stars in M17

open access: yes, 2016
The formation process of massive stars is still poorly understood. Massive young stellar objects (mYSOs) are deeply embedded in their parental clouds, they are rare and thus typically distant, and their reddened spectra usually preclude the determination
Bik, Arjan   +8 more
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Dark stars at the Galactic centre - the main sequence [PDF]

open access: yes, 2008
In regions of very high dark matter density such as the Galactic centre, the capture and annihilation of WIMP dark matter by stars has the potential to significantly alter their evolution.
Allen   +100 more
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

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