Results 61 to 70 of about 4,192,840 (340)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Recent Reacceleration of the Local Bubble Revealed by Kinematics of Young Star Associations
The Astrophysical Journal LettersThe low-density region of the interstellar medium where the Sun is located is known as the Local Bubble, a cavity filled with high-temperature and low-density plasma that may be created by a series of supernova (SN) explosions over the past 14 Myr ...
Guang-Ya Zeng +4 more
doaj +1 more source
Timescale of Mass Accretion in Pre-Main-Sequence Stars
, 2009 We present initial result of a large spectroscopic survey aimed at measuring the timescale of mass accretion in young, pre-main-sequence stars in the spectral type range K0 - M5.
Allen +51 more
core +1 more source
Improved $u'g'r'i'z'$ to $UBVR_CI_C$ Transformation Equations for Main Sequence Stars [PDF]
, 2006 We report improved transformation equations between the $u'g'r'i'z'$ and $UBVR_CI_C$ photometric systems. Although the details of the transformations depend on luminosity class, we find a typical rms scatter on the order of 0.001 magnitude if the sample ...
Christopher T. Rodgers +7 more
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Astrophysical JournalThe surface magnetic fields of pre-main-sequence stars and zero-age main-sequence stars are notably strong, resulting in the generation of numerous spots and the emission of bright chromospheric lines.
Mai Yamashita, Yoichi Itoh, Shin Toriumi
doaj +1 more source
An HST Study of the Substellar Population of NGC 2024
The Astrophysical Journal, 2023 We performed an HST/WFC3-IR imaging survey of the young stellar cluster NGC 2024 in three filters probing the 1.4 μ m H _2 O absorption feature, characteristic of the population of low-mass and substellar-mass objects down to a few Jupiter masses.
Massimo Robberto +8 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Astrophysical JournalTidal interactions are one of the primary drivers of orbital evolution for massive planets with short orbital periods. Tidal dissipation within host stars can cause the orbits of such planets to decay.
Noah Sodickson, Samuel Grunblatt
doaj +1 more source