Results 81 to 90 of about 3,957,653 (321)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Nitrogen chronology of massive main sequence stars

, 2012
Rotational mixing in massive main sequence stars is predicted to monotonically increase their surface nitrogen abundance with time. We use this effect to design a method for constraining the age and the inclination angle of massive main sequence stars ...
A. de Koter, Brott, Brott, Buonanno, Charbonnel, de Mink, Dufton, Endal, Evans, Evans, Heger, Hubeny, Hunter, Hunter, Hunter, Hunter, I. Brott, K. Köhler, M. Borzyszkowski, Maeder, Maeder, Meynet, Meynet, Mokiem, N. Langer, Przybilla, Salpeter, Sana, Schaerer, Vink, Vink, Vink   +31 more
core   +2 more sources

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Molecular line emissions from pre main sequence objects [PDF]

, 1997
We present some preliminary results obtained with the LWS G.T. programme on the study of young objects driving molecular outflows. In particular, we discuss the importance of molecular emission in these sources and address the role of the H20 ...
Benedettini, M., Caux, E., Ceccarelli, M. C., Clegg, P. E., Correia, J. C., di Giorgio, A. M., Giannini, T., Griffin, M. J., Leeks, S. J., Liseau, R., Lorenzetti, D., Molinari, S., Nisini, B., Saraceno, P., Smith, H., Spinoglio, L., Tomassi, E., White, G. J.   +17 more
core  

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Spectral Variability of Herbig Ae Star V1295, Aquila

Galaxies
This article presents the results of long-term spectral studies of the unusual Herbig Ae star V1295 Aql. The variability in the spectrophotometric parameters of the emission and absorption components of the hydrogen lines Hα, Hβ, and D Na I—and of ...
Hemayil Adigozalzade, Silva Jarvinen, Swetlana Hubrig, Ulviyya Bashirova, Nariman Ismailov   +4 more
doaj   +1 more source

Summarized effective temperatures scale of main sequence stars and substars

Вісник Астрономічної школи, 2013
The generalized scale of effective temperatures (T_eff) for substars and main sequence stars in the interval spectral types Sp = O8V ÷ T9,5V. Determined the dependence of effective temperatures T_eff from spectral code C_Sp for Sp = O8V ÷ T9,5V ...
M. A. Babenko, V. A. Zakhozhay
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Evolution of Stars toward the Main Sequence

Journal of Mathematical and Fundamental Sciences, 2019
. A review on the knowledge of the stellar evolution toward the main sequence is presented. This is the period during which the stars evolve from the beginning of their formation to the phase of stabilization on the main sequence where nuclear reactions ...
B. Hidajat
doaj  

Does Metallicity Affect the Protoplanetary Disk Fraction? Answers from the Outer Milky Way

The Astrophysical Journal
The role of metallicity in shaping protoplanetary disk evolution remains poorly comprehended. This study analyzes the disk fraction of 10 young (0.9–2.1 Myr) and low-metallicity (0.34–0.83 Z _⊙ ) clusters located in the outer Milky Way with ...
Sudeshna Patra, Jessy Jose, Neal J. Evans II   +2 more
doaj   +1 more source