Results 211 to 220 of about 928,468 (309)

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

Not all reflection is equal: Reflective practice, not self‐reflection, correlates with Indonesian medical students' professional identity formation

open access: yesMedical Education, EarlyView.
Abstract Background Professional identity formation (PIF) plays a significant role in the development of medical students, with reflection expected to help learners align their personal values with the expectations of the profession. While theoretical models propose that reflection and PIF advance hand in hand, empirical studies suggest that the ...
Indah Puspasari Kiay Demak   +6 more
wiley   +1 more source

Bridging data silos to holistically model plant macrophenology

open access: yesNew Phytologist, EarlyView.
Summary Phenological response to global climate change can impact ecosystem functions. There are various data sources from which spatiotemporal and taxonomic phenological data may be obtained: mobilized herbaria, community science initiatives, observatory networks, and remote sensing.
Lizbeth G. Amador   +9 more
wiley   +1 more source

#9. Inhibition of the fatty acid binding proteins (FABPs) in myeloma cells modifies their lipid composition

open access: yesJournal of Bone Oncology
Michelle Karam   +5 more
doaj   +1 more source

Seeing herbaria in a new light: leaf reflectance spectroscopy unlocks trait and classification modeling in plant biodiversity collections

open access: yesNew Phytologist, EarlyView.
Summary Reflectance spectroscopy is a rapid method for estimating traits and discriminating species. Spectral libraries from herbarium specimens represent an untapped resource for generating broad phenomic datasets across space, time, and taxa. We conducted a proof‐of‐concept study using trait data and spectra from herbarium specimens up to 179 yr old,
Dawson M. White   +6 more
wiley   +1 more source

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