Results 121 to 130 of about 1,301 (285)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Conformity Evaluation of Afinion 2 Analyzer Maintainability: Compliance Practicality for Philippine National Standard PNS ISO 15189:2013 Accreditation. [PDF]
Acta Med Philipp, 2023 Dayrit GB +5 more
europepmc +1 more source
Measuring Maintainability Index of a Software Depending on Line of Code Only
IOSR Journal of Computer Engineering, 2014 Maintainability Index (MI) has been proposed to calculate a single number that expresses the maintainability of a system. MI is calculated as a factored formula consisting of Lines of Code (LOC), Cyclomatic Complexity (CC)and Halstead Volume (HV). In this paper, we present a new method to find MI with respect to LOC only.
openaire +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Inteligencia ArtificialWe investigate whether Large Language Models (LLMs) can refine the given codebase of an optimization algorithm without requiring specialized user expertise. This is in contrast to works that study optimization algorithm code generation from scratch.
Camilo Chacón Sartori, Christian Blum
doaj
Strategies for maintaining the health of students with different body mass index
Siberian Journal of Life Sciences and AgricultureBackground. The main focus in maintaining health is on harmonizing lifestyle. Students with different body weights may have differences in physical activity, nutrition, daily routine, and sleep quality. Identifying negative lifestyle trends will help eliminate them and improve health. Purpose. To identify risk factors of the lifestyle of students with
Ol'ga A. Firsova +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Generating project value through design for reliability: on the development and implementation of a potential value framework [PDF]
, 2007 The current trend to economically exploit deepwater hydrocarbon reserves is to reduce the capital expenditure; accomplished by deploying subsea equipment.
Woods, K. B. W.
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source