Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Demonstrating the interplay between resilience, engagement, and wellbeing among Chinese teachers: the mediating role of self-efficacy. [PDF]
Yang J.
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Bionic Technology in Prosthetics: Multi-Objective Optimization of a Bioinspired Shoulder-Elbow Prosthesis with Embedded Actuation. [PDF]
Jiang J, Chen G, Wang X, Yan H.
europepmc +1 more source
Federated microservices architecture with blockchain for privacy-preserving and scalable healthcare analytics. [PDF]
Harshith M +6 more
europepmc +1 more source
Low-cost social robot designs for education: a review. [PDF]
Rutatola EP +4 more
europepmc +1 more source
ThongPaDisp: An open-source 3D-printed shuttlecock dispenser using a Grip-Gate-Push mechanism. [PDF]
Saeeab T, Phiphitphibunsuk W.
europepmc +1 more source
Bi-level optimization of shared manufacturing service composition based on improved NSGA-II. [PDF]
Wang Y, Liu P.
europepmc +1 more source
Role of Aircraft Feedback Information in Developing Maintainability Allocation Index
openaire +1 more source
Parsing GTF and FASTA files using the eccLib Library. [PDF]
Chady T, Filutowska ZK.
europepmc +1 more source

