Results 51 to 60 of about 1,711,572 (219)

Maintenance Economics of Widebody Aircraft: Comparative Cost and Reliability Analysis of the Boeing 787 and Airbus A350 [PDF]

Journal of South Asian Logistics and Transport
Next-generation wide-body aircraft, such as the Boeing 787 and Airbus A350, incorporate advanced composite structures and predictive maintenance systems; however, limited research has examined how these innovations affect maintenance costs and ...
A. C. Dela Peña, M. A. M. Ganal, E. B. Tiansay   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Surplus value quantification of overdue medical devices based on Kohonen network algorithm

Scientific Reports
With the continuous updating and progress of medical equipment, the overdue medical device has problems such as management difficulties, resource waste, and potential security risks.
Xiaomei Tan, Yajie Mao, Jin Zhang, Jiansheng Li   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Mechanism study on the regulation of autophagy and oxidative stress through SIRT1/PI3K/AKT pathway by Liuwei Dihuang pill to improve ovarian function

Journal of Ovarian Research
Objective This study aimed to examine the preventive impact of Liuwei Dihuang pill (LWDH) on ovarian injury and to elucidate its mechanism through in vivo and in vitro tests.
Jiawen Zhong, Guoxia Lan, Xiaoqing Ma, Wenyan Zhang, Bo Jiang, Ling Qin, Xiaorong Li, Yan Nian   +7 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Numerical investigation of aerodynamic performance in a morphing wing with flexible leading edge using computational fluid dynamics

Journal of Engineering and Applied Science
In this study, a numerical investigation into the sustained aerodynamic performance of a morphing wing equipped with a flexible leading edge, employing a 2-dimensional NACA0012 airfoil configuration, is conducted.
Junjie Shi, Fei Han, Taorui Li, Chao Liu
doaj   +1 more source

A computer vision approach with OpenCV and deep learning for determining inductance in planar coils

Vojnotehnički Glasnik
Introduction/purpose: In the realm of development and use of computer vision and AI methodologies, this research introduces a combination and advanced method using YOLOv9, a deep learning concept of whole image processing in one pass through a ...
Younes Benazzouz, Djilalia Guendouz
doaj   +1 more source