Results 121 to 130 of about 79,566 (278)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Maintenance modelling of a major hospital complex [PDF]

By its nature, building maintenance requires an ability to respond to a demand that is random in time, random in nature and random in location. This in turn creates complex operational and logistical problems for management, specially if the property ...
Alzubaidi, HJ
core   +1 more source

Identifying and Analyzing Investment Risks in Hospital Wastewater Infrastructure Using the FMEA Method [PDF]

بیمارستان
Background and purpose: Hospital wastewater infrastructure is critical for safeguarding public health and protecting the environment. Deficiencies in the management of these systems can precipitate severe public health and environmental crises.
Abbas Jahangiri
doaj  

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Assessment of the Feasibility and Potential Impact of IoT-Based Predictive Maintenance for HVAC Systems in Public Hospitals in Nigeria

Effective heating, ventilation, and air-conditioning (HVAC) performance is critical to thermal comfort, operational efficiency and better performance of installed equipment in healthcare facilities.
Titus Ilupeju
core   +1 more source

The role of bioengineer in hospital upkeep and development

, 2007
In Italy, hospitals of different dimensions have been equipped, in the last years, with a clinical engineering structure that is leaded by a bioengineer whose main role is management of bioinstrumentation in terms of planning for purchases and ...
BIFFI GENTILI, GUIDO, DORI, FABRIZIO, IADANZA, ERNESTO   +2 more
core   +1 more source

Gantry-period-guided modulation factor selection in helical tomotherapy: effects on delivery efficiency, dosimetry and verification accuracy

Frontiers in Oncology
PurposeTo explore a gantry-period-guided strategy for identifying a lower useful modulation factor (MF) in helical tomotherapy under fixed field width and pitch.MethodsTwenty previously treated cases from head, head-and-neck, abdomen and pelvis were ...
Xiaoli Jin, Tianhui Gao, Xiangqian Liu, Hailiang Zhang, Xin Yang, Xia Zhang   +5 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Proposal for management and preventive maintenance of medical-hospital equipment based on the criticality methodology.

, 2023
Clinical engineering is a field of biomedical engineering responsible for managing the technologies present in healthcare facilities. The main objective of the management process is to guarantee the quality of what is being worked on, that is, it is ...
Carvalho, Auana Paola Silva
core  

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source