Results 141 to 150 of about 660,261 (307)

A process model of maintenance with reuse: an investigation and an implementation abstract [PDF]

open access: yes, 1997
Sixty to eighty per cent of the software life-cycle cost is spent on the software maintenance phase because software maintenance is usually more difficult than original development and legacy systems are generally large and complex.
Kwon, Oh Cheon
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Cloud control platform of intelligent and networked public transport based on BIM technology

open access: yesJournal of Highway and Transportation Research and Development
To ensure the efficiency and safety of citizens’ travel while enhancing the management level of urban public transportation, this paper constructs an intelligent bus control platform deployed on the Internet, leveraging Building Information Modeling (BIM)
Xitong Xia
doaj   +1 more source

A value-centric decision making framework for maintenance services outsourcing [PDF]

open access: yes, 2011
The shift in mindset of decision makers, from maintenance being a “necessary evil” and “cost centre” to a “profit contributor” in manufacturing companies has driven outsourced maintenance suppliers to employ value-centric approaches in order to design
Toossi, Amir
core  

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai   +5 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Detection of conveyor belt defects using unified diagnostic criteria.

open access: yesГорное оборудование и электромеханика
Relevance of the work. This work covers the results of research in the field of monitoring the parameters of mechanical vibrations of crushing and screening equipment, obtained using new unified diagnostic criteria developed taking into account the ...
Gerike P.B., Gericke B.L.
doaj   +1 more source

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