Results 131 to 140 of about 564,395 (306)

Optimization of Metro Tunnel Maintenance Strategy Based on Improved Particle Swarm Algorithm

Chengshi guidao jiaotong yanjiu
[Objective] Maintenance strategy is the key factor influencing the lifetime service performance and maintenance cost of metro tunnel. Therefore, it is essential to develop more suitable optimization algorithms for maintenance strategies.
Yining GU, Qing AI, Yong YUAN
doaj   +1 more source

Improving workforce scheduling of aircraft line maintenance at Sabena Technics. [PDF]

This paper presents our application of a visualization tool and optimization model based on mixed-integer linear programming to solve a workforce staffing and scheduling problem at Sabena Technics, a major aircraft maintenance company in Belgium. We used
Belien, Jeroen, Cardoen, Brecht, Demeulemeester, Erik   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Optimal Trajectory Optimization of 7R Robot for Space Maintenance Operation

IEEE Access
This paper studies the optimal trajectory optimization of a space robot for maintenance operations. A new trajectory planning algorithm is proposed to solve the problems of low maintenance efficiency and poor stationarity of space robots on-orbit ...
Qidong Li, Hehua Ju, Pengfei Xiao, Feifei Chen, Fei Lin   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A Transformer Maintenance Interval Optimization Method Considering Imperfect Maintenance and Dynamic Maintenance Costs

Applied Sciences
As one of the most critical components of the power grid system, transformer maintenance strategy planning significantly influences the safe, economical, and sustainable operation of the power system. Periodic imperfect maintenance strategies have become
Jianzhong Yang, Hongduo Wu, Yue Yang, Xiayao Zhao, Hua Xun, Xingzheng Wei, Zhiqi Guo   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

OPTIMIZATION RESEARCH OF PREVENTIVE MAINTENANCE STRATEGY ON THE CATENARY SYSTEM BASED ON RELIABILITY CONSTRAINTS

Jixie qiangdu, 2016
Optimization research on reliability of the catenary system and preventive maintenance strategy is the key to ensure the safe operation of the electrical railway.
LIU Huan, LIU ZhiGang, JIANG Jing
doaj  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source