Results 231 to 240 of about 5,027,933 (297)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

STRATEGIES OF THE MAINTENANCE ACTIVITY

ANNALS OF THE ORADEA UNIVERSITY. Fascicle of Management and Technological Engineering., 2013
openaire   +1 more source

Expected clinical and patient-centered outcomes associated with different rehabilitation strategies for severe maxillary atrophy: an international cross-sectional survey. [PDF]

Front Oral Health
Gasparini G, Todaro M, Papa E, Amato MG, De Angelis P, Moro A, Lajolo C, Nicolai G, Rella E, Boniello R, Moix Gil X, Staderini E, Gasparini S, Perquoti F, Spinozzi G, Santoro V, Di Carlo D, Ascani G, Manicone PF, Foresti MD, Perugini M, Azzuni F, Collaborative Working Group, Saponaro G.   +23 more
europepmc   +1 more source

A simple strategy for enhancing NADPH-dependent biocatalysis <i>via</i> phosphate analogue-mediated maintenance of the NADPH pool. [PDF]

RSC Adv
Liu R, Liu J, Zhang R, Kuang X, Ma Z, Zhang Q, Xu X, Cheng X, Yang J.   +8 more
europepmc   +1 more source

Observation versus maintenance immunotherapy after PD-1-induced clinical complete response in dMMR/MSI-H colorectal cancer managed non-operatively: a multicenter cohort study. [PDF]

J Immunother Cancer
Gao X, Wang Q, Zhang Z, He F, Ding Y, Zhang L, Pei D, Niu S, Chen H, Sun R, Yao Y, Han W, Chen Y, Chang H, Xiao W, Li L, Zhang R, Gao Y.   +17 more
europepmc   +1 more source

Reducing medical equipment downtime using Lean Six Sigma: a quality improvement project at Suhul Hospital, Shire. [PDF]

BMJ Open Qual
Gebremariyam HM.
europepmc   +1 more source

Income Maintenance Strategies

, 1994
openaire   +1 more source