Results 231 to 240 of about 50,108 (261)

Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression

Advanced Science, EarlyView.
This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng, Shuang Cai, Chen Guo, Shaker Khan, Lefan Liu, Qiong Tian, Zhiyuan Ma, Jian Zhang, Lingyu Zhao   +8 more
wiley   +1 more source

Biofortification of baby corn: Integrating agronomic and genetic approaches to address zinc micronutrient deficiencies - global perspectives and future challenges. [PDF]

Front Plant Sci
Mallipeddi S, B V, M SR.
europepmc   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

Genetic dynamics drive maize growth and breeding. [PDF]

Genome Biol
Wu C, Geng Z, Li W, Ye J, Hao X, Xu J, Jin M, Wu X, Du Y, Chen Y, Ma C, Gao Y, Chen Y, Xie T, Gui S, Chen Y, Luo J, Liu Y, Yang W, Yan J, Yang W, Xiao Y.   +21 more
europepmc   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Optimum recombination rates for genetic gains in simulated recurrent selection in empirical maize populations. [PDF]

Plant Genome
Anilkumar C, Bernardo R.
europepmc   +1 more source

Identification of <i>ZmP5CS</i> Gene Family and Functional Analysis of <i>ZmP5CS4</i> Under Salt Tolerance in Maize. [PDF]

Plants (Basel)
Zhang C, Sun L, Guo J, Dong J, Jin F, Zhou X, Liu X, Liu C, Li X.   +8 more
europepmc   +1 more source

Kangnongyu8009: a new high-yield maize variety developed through amalgamation of temperate and tropical germplasm. [PDF]

Mol Breed
Guo X, Liu P, Wang D, Tu L, Wang A, Zhu Y, Yan P, Zhang Z, Peng X, Tang J, Chen Z.   +10 more
europepmc   +1 more source

Integrative transcriptomics and defense-related gene family analysis reveals key genes for maize resistance to fall armyworm. [PDF]

BMC Plant Biol
Hu Y, Wang T, Du J, Yu H, Wu D.
europepmc   +1 more source

Maize variety traits for different needs: using the means-end chains method to identify preferences and perceived benefits among smallholder farmers in Kenya. [PDF]

Food Secur
Garcia-Medina M, Kilwinger F, Almekinders C, Donovan J.   +3 more
europepmc   +1 more source