Results 51 to 60 of about 19,306 (297)

A compendium of Technologies, Practices, Services and Policies for Scaling Climate Smart Agriculture in Odisha (India) [PDF]

, 2020
Stakeholders engaged in agricultural research for development (AR4D) are increasingly tackling risks associated with climate change in smallholder systems.
Biswal, Sabyasachi, Jat, Mangi Lal, Khatri-Chhetri, Arun, Pathak, Himanshu, Rana, Dharamvir Singh, Sharma, Sheetal   +5 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Changes of Weight and in-Kernel Content Values of Maize Hybrids (Occitan, Colomba, DK-471) as a Result of Damaging dy European Corn Borer. Kukorica hibridek (Occitan, Colomba, DK-471) súly- és beltartalmi érték változása a kukoricamoly (Ostrinia nubilalis Hbn.) károsítása következtében. [PDF]

, 2002
ÖSSZEFOGLALÁS Vizsgálatunkat 2001-ben két tábla három különböző hibriddel elvetett állományában vizsgáltuk véletlenszerű mintaterek kijelölésével. Első felmérésünket egy 120 ha-os COLOMBA és OCCITAN, míg a második vizsgálatunkat egy 50 ha-os DK-471-es
Keszthelyi, Sándor, Takács, András
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Effects of Nitrogen Fertilizer Management on Stalk Lodging Resistance Traits in Summer Maize

Agriculture, 2022
Stalk lodging in Huang-Huai-Hai summer maize is a serious problem that reduces maize yields and precludes the use of mechanical grain harvesting equipment.
Juan Zhai, Yuanmeng Zhang, Guoqiang Zhang, Ming Tian, Ruizhi Xie, Bo Ming, Peng Hou, Keru Wang, Jun Xue, Shaokun Li   +9 more
doaj   +1 more source

Evaluation of maize variety suitability on lodging in target environments based on GIS

Annals of GIS, 2011
Lodging is one of the major problems in maize production which causes severe yield loss every year all over the world. In the present study, the lodging suitability of different maize varieties in target growing environments was investigated based on geographical information science.
Chunqiao Mi, Xiaodong Zhang 0016, Shaoming Li, Jianyu Yang 0005, Dehai Zhu   +4 more
openaire   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Local auxin biosynthesis regulates brace root angle and lodging resistance in maize

New Phytologist, 2023
Summary Root lodging poses a major threat to maize production, resulting in reduced grain yield and quality, and increased harvest costs. Here, we combined expressional ...
Zhigang Zheng, Baobao Wang, Chuyun Zhuo, Yurong Xie, Xiaoming Zhang, Yanjun Liu, Guisen Zhang, Hui Ding, Binbin Zhao, Manqing Tian, Miaoyun Xu, Dexin Kong, Rongxin Shen, Qing Liu, Guangxia Wu, Junfei Huang, Haiyang Wang   +16 more
openaire   +3 more sources