Results 231 to 240 of about 1,659,809 (298)

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

open access: yesAdvanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao   +4 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Nutritional Modulation of Impaired Blood-Brain Barrier Integrity and Function in Major Depression. [PDF]

open access: yesInt J Mol Sci
Adzic M   +6 more
europepmc   +1 more source

Simvastatin as Add-On Treatment to Escitalopram in Patients With Major Depression and Obesity: A Randomized Clinical Trial.

open access: yesJAMA Psychiatry
Otte C   +29 more
europepmc   +1 more source

Evidence map of nutrient interventions for major depression: a systematic review protocol. [PDF]

open access: yesSyst Rev
Zhang D   +10 more
europepmc   +1 more source

Increased insular functional connectivity during repetitive negative thinking in major depression and healthy volunteers. [PDF]

open access: yesPsychol Med
Edwards LS   +8 more
europepmc   +1 more source

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