P01.105 Alpha-1-acid glycoprotein and suicidality in major depressive disorder [PDF]
E. Nieto+4 more
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Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop
The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu+22 more
wiley +1 more source
Tianeptine and paroxetine in major depressive disorder, with a special focus on the anxious component in depression: an international, 6‐week double‐blind study† [PDF]
J.P. Lépine+6 more
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In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao+13 more
wiley +1 more source
Early onset major depressive disorder [PDF]
William Fleisher, Laurence Y. Katz
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The Interplay between the Gut and Ketogenic Diets in Health and Disease
This review synthesizes current knowledge on the interaction between ketogenic diets and the gut, covering gut physiology, intestinal immunity, and the gut microbiome. It explores innovative methods for tailoring the diet to maximize benefits while reducing side effects. Emphasis is placed on gut‐mediated mechanisms as a critical interface between diet
Chunlong Mu, Jong M. Rho, Jane Shearer
wiley +1 more source
Response in Relation to Baseline Anxiety Levels in Major Depressive Disorder Treated with Bupropion Sustained Release or Sertraline [PDF]
A. John Rush
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Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang+13 more
wiley +1 more source
A double-blind, randomized parallel-group, efficacy and safety study of intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) versus imipramine in patients with major depressive disorder [PDF]
P. Pancheri+2 more
openalex +1 more source
Phonologically-based biomarkers for major depressive disorder
Of increasing importance in the civilian and military population is the recognition of major depressive disorder at its earliest stages and intervention before the onset of severe symptoms.
Trevino Andrea+2 more
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