Results 181 to 190 of about 533,533 (336)

Biological Aging Acceleration in Major Depressive Disorder: A Multi-Omics Analysis. [PDF]

Aging Cell
Diniz BS, Zhao S, Drouard G, Vuoksimaa E, Ollikainen M, Lenze EJ, Xu M, Fortinsky RH, Kuchel GA, Kaprio J, Kuo CL.   +10 more
europepmc   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Investigating the causal role of circulating metabolites in major depressive disorder. [PDF]

Gen Psychiatr
Fu L, Baranova A, Cao H, Zhang F.
europepmc   +1 more source

Supplementary Material for: Neuropsychological Assessments of Cognitive Impairment in Major Depressive Disorder: A Systematic Review and Meta-Analysis with Meta-Regression

Rhee T.G., Shim S.R., Manning K.J., Tennen H.A., Kaster T.S., G D’Andrea, Forester B.P., Nierenberg A.A., McIntyre R.S., Steffens D.C.   +9 more
openalex   +1 more source

A Multifunctional Polar Amino Acid for Mixed Tin‐Lead Perovskites and All‐Perovskite Tandems

Advanced Science, EarlyView.
AsnCl improves film orientation and crystallinity, suppresses Sn4+ and PbI2 defects, and prolongs carrier lifetimes, enabling a 22.54% efficiency and enhanced stability in Sn–Pb perovskite solar cells. The AsnCl‐treated tandem device achieves a steady‐state PCE of 28.24%, underscoring the effectiveness of additive molecular engineering for high ...
Jin Zhou, Hongsen Cui, Chen Wang, Dexin Pu, Lishuai Huang, Shun Zhou, Guang Li, Qingxian Lin, Shining Zhang, Weiqing Chen, Guojia Fang, Weijun Ke, Weiwei Meng   +12 more
wiley   +1 more source

Affective and cognitive theory of mind in posttraumatic stress, major depressive, and somatic symptom disorders: Association with childhood trauma

, 2022
K. Seitz, Nicola Ehler, Marius Schmitz, Sara Elena Schmitz, Isabel Dziobek, Sabine C. Herpertz, Katja Bertsch   +6 more
openalex   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Temperament and major depressive disorder

Annals of General Psychiatry, 2010
Mneimneh Zeina, Yeretzian Joumana S, Salamoun Mariana M, Karam Elie G, Karam Aimee N, Fayyad John   +5 more
doaj   +1 more source

Positive memory enhancement training for individuals with major depressive disorder [PDF]

, 2018
De Raedt, Rudi, Hall, K. A. A., Joormann, Jutta, Timpano, Kiara R   +3 more
core   +2 more sources

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source