Results 211 to 220 of about 827,746 (374)

Autonomous Neurobiological Pathways to Late-Life Major Depressive Disorder Clinical and Pathophysiological Implications [PDF]

, 2002
Anand Kumar, Jim Mintz, Warren Bilker, Gary Gottlieb   +3 more
openalex   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Comorbid anxiety predicts lower odds of depression improvement during smartphone-delivered psychotherapy [PDF]

arXiv
Comorbid anxiety disorders are common among patients with major depressive disorder (MDD), and numerous studies have identified an association between comorbid anxiety and resistance to pharmacological depression treatment. However, the impact of anxiety on the effectiveness of non-pharmacological interventions for MDD is not as well understood.
arxiv  

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

Advanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song, Xiangxu Wang, Luqing Ha, Lamei Hu, Shuyuan Mei, Yue Liang, Yujie Zhao, Xingyin Yang, Qingyu Zhang, Yuanzhang Zhou, Jianhua Ding, Yan Liu, Qigang Zhou, Feng Han, Gang Hu, Ming Lu   +15 more
wiley   +1 more source

Breaking the Stigma! Unobtrusively Probe Symptoms in Depression Disorder Diagnosis Dialogue [PDF]

arXiv
Stigma has emerged as one of the major obstacles to effectively diagnosing depression, as it prevents users from open conversations about their struggles. This requires advanced questioning skills to carefully probe the presence of specific symptoms in an unobtrusive manner.
arxiv  

Autobiographical memory specificity and the course of major depressive disorder [PDF]

, 2002
Frenk Peeters, Ineke Wessel, Harald Merckelbach, Miranda Boon-Vermeeren   +3 more
openalex   +1 more source

Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States

JAMA psychiatry, 2018
D. Hasin, D. Hasin, Aaron L Sarvet, J. Meyers, T. Saha, W. J. Ruan, Malka Stohl, B. Grant   +7 more
semanticscholar   +1 more source

Aromaticity‐Dependent Memristive Switching

Advanced Electronic Materials, EarlyView.
The article describes a resistive switching mechanism based on the creation of virtual filaments. Research consists of experimental and theoretical data supporting the theory that resistance of the memristor can be modulated by a redox‐induced aromaticity change of a working material.
Ewelina Cechosz, Lulu Alluhaibi, Tomasz Mazur, Andrzej Sławek, Nanjan Pandurangan, Konrad Szaciłowski   +5 more
wiley   +1 more source

Assessing ML Classification Algorithms and NLP Techniques for Depression Detection: An Experimental Case Study [PDF]

arXiv
Depression has affected millions of people worldwide and has become one of the most common mental disorders. Early mental disorder detection can reduce costs for public health agencies and prevent other major comorbidities. Additionally, the shortage of specialized personnel is very concerning since Depression diagnosis is highly dependent on expert ...
arxiv  

Breaking the Stigma: Major Depressive Disorder [PDF]

, 2019
Major Depressive Disorder (MDD) is a mood and mental disorder affecting the brain; it is caused by the reduction of three monoamine neurotransmitters: serotonin, norepinephrine, and dopamine (Rot, M. A., Mathew, S. J., & Charney, D. S. 2009).
Cox, Joanna
core   +1 more source