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Major depressive disorder

Nature Reviews Disease Primers, 2023
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and physical and cognitive symptoms. People with MDD can have reduced quality of life owing to the disorder itself as well as related medical comorbidities, social factors, and ...
Wolfgang Marx   +6 more
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Major Depressive Disorder and Depressive Symptoms [PDF]

open access: possible, 2022
In professional sport, the mental health of elite athletes is a major concern. Given its high prevalence and the potential for multifaceted and severe consequences, major depressive disorder is one of the greatest concerns with respect to the mental health of elite athletes.
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Major Depressive Disorder

New England Journal of Medicine, 2008
Depression is related to the normal emotions of sadness and bereavement, but it does not remit when the external cause of these emotions dissipates, and it is disproportionate to their cause. Classic severe states of depression often have no external precipitating cause.
R H, Belmaker, Galila, Agam
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Depression and memory in major depressive disorder

The Journal of Neuropsychiatry and Clinical Neurosciences, 1991
The relationship between memory function and depression was examined in 23 patients who met DSM-III criteria for major depression. All patients were unmedicated at the time of examination, which included the Wechsler Memory Scale, Minnesota Multiphasic Personality Inventory-Depression Scale (MMPI-D), and Hamilton Depression Rating Scale (HDRS ...
R A, Bornstein   +2 more
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P300 in major depressive disorder

Psychiatry Research, 1985
This study presents evidence of differences in the P3 (P300) component of the event-related potential (ERP) between major depressed patients and normal controls. ERPs were collected to visual stimuli in a modified continuous performance task. For each subject, the peak of the P3 (also N2 and P2) component was identified for four different electrode ...
B C, Diner, P J, Holcomb, R A, Dykman
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Recidivism in Major Depressive Disorder

Psychotherapy and Psychosomatics, 2010
Background: While recidivism has been well studied in psychotic disorders, little has specifically been done to determine what differences exist between patients admitted multiple times compared with once for major depressive disorder (MDD). Method: The records of patients admitted with MDD to a large military medical center were reviewed during the ...
L A, Labbate, M E, Doyle
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Major depressive disorder: Biomarkers and biosensors

Clinica Chimica Acta, 2023
Depressive disorders belong to highly heterogeneous psychiatric diseases. Loss of in interest in previously enjoyed activities and a depressed mood are the main characteristics of major depressive disorder (MDD). Moreover, due to significant heterogeneity in clinical presentation and lack of applicable biomarkers, diagnosis and treatment remains ...
Dadkhah, Masoomeh   +5 more
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The genetics of major depressive disorder

Current Psychiatry Reports, 2000
There is consistent evidence that major depression is familial and population-based twin studies as well as hospital register-based twin studies find substantial heritability. However, there is also a large proportion of variation in liability left to be explained by nongenetic factors.
G S, Malhi, J, Moore, P, McGuffin
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