Results 81 to 90 of about 832,143 (393)

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms? [PDF]

, 2010
Mental disorders are a major cause of long-term disability and are a direct cause of mortality, with approximately 800.000 individuals dying from suicide every year worldwide - a high proportion of them related to major depressive disorder (MDD)^1 ...
Andrew Fagan, Angela Carballedo, Danusia Lisiecka, Dermot Kelleher, Ian Daly, James Meaney, Thomas Frodl, Thomas Frodl, Yolande Ferguson   +8 more
core   +3 more sources

Unit Cost of Major Depressive Disorder in Psychiatric Ward, Siriraj Hospital

Siriraj Medical Journal, 2005
Objective: To study the unit cost of treatment of major depressive disorder patients who were admitted into the psychiatric ward in Siriraj Hospital in fiscal year 2001. Methods: This is a retrospective study from the view of care providers.
Suwit Charoensak, Sunanta Chantarujikapong, Suthichai Cherdsuwan, Kanokkan Ontale   +3 more
doaj  

Gutted! Unraveling the Role of the Microbiome in Major Depressive Disorder.

Harvard Review of Psychiatry, 2020
Microorganisms can be found in virtually any environment. In humans, the largest collection of microorganisms is found in the gut ecosystem. The adult gut microbiome consists of more genes than its human host and typically spans more than 60 genera from ...
T. Bastiaanssen, S. Cussotto, M. Claesson, G. Clarke, T. Dinan, J. Cryan   +5 more
semanticscholar   +1 more source

The Mistreatment of Major Depressive Disorder [PDF]

The Canadian Journal of Psychiatry, 2014
Objective: To examine the effects of classification on treatment in major depressive disorder (MDD). Method: This is a narrative review. Results: MDD is a highly heterogeneous category, leading to problems in classification and in specificity of treatment. Current models classify all depressions within a single category.
openaire   +3 more sources

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies. [PDF]

In a genome-wide association study (GWAS) meta-analysis of 688,808 individuals with major depression (MD) and 4,364,225 controls from 29 countries across diverse and admixed ancestries, we identify 697 associations at 635 loci, 293 of which are novel ...
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk   +1 more
core   +1 more source

Major depressive disorder, personality disorders and coping strategies are independent risk factors for lower quality of life in non-metastatic breast cancer patients. [PDF]

, 2015
International audienceObjective: To identify risk factors for lower quality of life (QOL) in non-metastatic breast cancer patients.Methods: Our study included 120 patients from the University Hospital Centers of Tours and Poitiers.
Aaronson, Al-Azri, Bakas, Bloom, Boureau, Brunault, Brunault, Burgess, Carver, Cousson-Gélie, Dolbeault, Duijsens, Elumelu, Enfoux, Fallowfield, Ferlay, Fillion, Fournier, Helms, Huang, Härtl, Härtl, Ivanauskienė, Janz, Kroenke, Lecrubier, Leplège, Melzack, Montazeri, Morrill, Naaman, Rachet, Reich, Ruo, Sheehan, Sundaresan, Wilson   +36 more
core   +4 more sources

Major Depressive Disorder: A General Overview [PDF]

SHS Web of Conferences
Major Depressive Disorder (MDD) has become a serious mental health problem with a lifetime prevalence of 15% to 20%. MDD is associated with significant morbidity, mortality, disability, and negative influence on patient's daily life This article is an ...
Wang Tianqi
doaj   +1 more source

CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani, Tsuyoshi Nakai, Yasuhiro Maeda, Reiko Ohdake, Atsuhiro Higashi, Toshiki Maeda, Ryunosuke Nagao, Sayuri Shima, Kazuya Kawabata, Akihiro Ueda, Mizuki Ito, Hirohisa Watanabe   +11 more
wiley   +1 more source