Results 81 to 90 of about 827,746 (374)

Gutted! Unraveling the Role of the Microbiome in Major Depressive Disorder.

Harvard Review of Psychiatry, 2020
Microorganisms can be found in virtually any environment. In humans, the largest collection of microorganisms is found in the gut ecosystem. The adult gut microbiome consists of more genes than its human host and typically spans more than 60 genera from ...
T. Bastiaanssen, S. Cussotto, M. Claesson, G. Clarke, T. Dinan, J. Cryan   +5 more
semanticscholar   +1 more source

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita, Neel Desai, Abigail R. Manning, Caitlin Pileggi, Sara Manning Peskin, Danielle K. Sandsmark, Dennis L. Kolson, Matthew K. Schindler   +7 more
wiley   +1 more source

Gene expression in major depressive disorder [PDF]

Molecular Psychiatry, 2015
The search for genetic variants underlying major depressive disorder (MDD) has not yet provided firm leads to its underlying molecular biology. A complementary approach is to study gene expression in relation to MDD. We measured gene expression in peripheral blood from 1848 subjects from The Netherlands Study of Depression and Anxiety.
Patrick F. Sullivan, Kai Xia, Anke R. Hammerschlag, Danielle Posthuma, Jay A. Tischfield, Y. Milaneschi, Rick Jansen, Fred A. Wright, Fred A. Wright, E.J.C. de Geus, A.T.F. Beekman, Wei Sun, N van der Wee, Vered Madar, Jouke-Jan Hottenga, Robert A. Schoevers, Brenda W.J.H. Penninx, Fei Zou, Dorret I. Boomsma, Jan Smit, Andrew Brooks, G van Grootheest, Gonneke Willemsen   +22 more
openaire   +7 more sources

Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan, Shravni Deshmukh, Mark Cummings, Aditi Doshi, Kourosh Rezania, Sally Freels, Gina Sawa   +6 more
wiley   +1 more source

Adiposity, depression and anxiety: interrelationship and possible mediators [PDF]

, 2019
OBJECTIVES: To explore the association between adiposity, major depressive disorder and generalized anxiety disorder, and to assess the role of inflammation, diet quality and physical activity in this association.
Assunção, Maria Cecília, Gomes, Ana Paula, Gonçalves, Helen, Howe, Laura D., Menezes, Ana M.B., Soares, Ana Luiza G., Wehrmeister, Fernando C.   +6 more
core   +6 more sources

Generalized Dilated CNN Models for Depression Detection Using Inverted Vocal Tract Variables [PDF]

arXiv, 2020
Depression detection using vocal biomarkers is a highly researched area. Articulatory coordination features (ACFs) are developed based on the changes in neuromotor coordination due to psychomotor slowing, a key feature of Major Depressive Disorder.
arxiv  

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients

PLoS ONE, 2020
Objective The economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non–treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li, Ling Zhang, Allitia DiBernardo, Grace Wang, John J. Sheehan, Kwan Lee, Johan Reutfors, Qiaoyi Zhang, Fernando A. Wilson   +8 more
doaj   +2 more sources

Exosomal let-7e, miR-21-5p, miR-145, miR-146a and miR-155 in Predicting Antidepressants Response in Patients with Major Depressive Disorder

Biomedicines, 2021
The intracellular microRNAs that negatively regulate Toll-like receptor 4 signaling pathways in peripheral blood mononuclear cells are associated with major depressive disorder (MDD). However, that the distribution of these microRNAs in exosomes could be
Yi-Yung Hung, Chen-Kai Chou, Yi-Chien Yang, Hung-Chun Fu, El-Wui Loh, Hong-Yo Kang   +5 more
doaj   +1 more source

Autobiographical Memories in Major Depressive Disorder [PDF]

Clinical Psychology & Psychotherapy, 2011
The objective of this research was to study the relation between the processing and recall of information in major depressive disorder. An autobiographical memory task was applied to 42 subjects with a diagnosis of major depressive disorder, 28 subjects with a diagnosis of panic disorder and 51 subjects without any psychological disorder.
Claúdio, Victor, Aurélio, João Garcez, Machado, Paulo P. P.   +2 more
openaire   +5 more sources