Results 91 to 100 of about 8,551,574 (247)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

A Typical report: Newsletter of the Special Education Section [Vol. 6, No. 2]

open access: yes, 1973
"February, 1973.""A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local school administrators and special education personnel. It is anticipated that this newsletter
Kansas. Special Education Administration Section.
core   +1 more source

An exploration of ways in which Waikato primary school principals address the multiple learning requirements of children with special educational needs [PDF]

open access: yes, 2014
Based on research evidence from New Zealand, England and the USA, it is likely that there could be an increasing number of students with special needs enrolling in New Zealand schools. This trend reinforces the need for an additional aspect to the usual
Symes, Rosemary
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The Special Education Instructional Paraprofessional in Kansas

open access: yes, 1970
"This project is funded by a grant through the United States Office of Education, Special Education Program, Grant G008530019."--Page [7 of 8].Who is a Special Education Instructional Paraprofessional? What is the History of the Paraprofessional?
Kansas. Special Education Paraprofessional Community College Program.
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Special consisting of engine no 2

open access: yes, 1887
A special consisting of engine number 2 and a coach passed over a portion of the MH&O Wednesday. The coach contained W. A. Thompson, assistant superintendent, David Sutton, acting master builder, C. H. V.

core   +1 more source

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