Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition. [PDF]
Cancer Res, 2011 Coloff JL +6 more
europepmc +1 more source
Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis. [PDF]
Oncotarget, 2017 Zhao Y +8 more
europepmc +1 more source
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species. [PDF]
Cell Rep, 2015 Zong H +18 more
europepmc +1 more source
P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells. [PDF]
Mol Carcinog, 2017 Babagana M +5 more
europepmc +1 more source
CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas. [PDF]
Haematologica, 2020 Chen L +11 more
europepmc +1 more source
Systematic Review and Network Meta-Analysis on Treating Hormone Receptor-Positive Metastatic Breast Cancer After CDK4/6 Inhibitors. [PDF]
Curr OncolPathak N +9 more
europepmc +1 more source
SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas. [PDF]
Cancer Cell, 2013 Chen L +14 more
europepmc +1 more source
Akt activation emulates Chk1 inhibition and Bcl2 overexpression and abrogates G2 cell cycle checkpoint by inhibiting BRCA1 foci. [PDF]
J Biol Chem, 2010 Tonic I, Yu WN, Park Y, Chen CC, Hay N.
europepmc +1 more source