Results 91 to 100 of about 723,548 (240)

Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]

, 2011
BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach, Brian Greenwood, Daniel Ansong, David Schellenberg, Jahit Sacarlal, Jennifer Evans, Johan Vekemans, Kevin Marsh, Kwaku Asante, Mary J Hamel, Nahya Salim, null null, Patricia Njuguna, Philip Bejon, Portia Kamthunzi, Samwel Gesase, Solange Soulanoudjingar, Walter Otieno, William Kabore   +18 more
core   +4 more sources

Identifying and characterizing high-risk populations in pilot malaria elimination districts in Madagascar: a mixed-methods study

Malaria Journal
Background In Madagascar, the districts of Antsirabe II, Faratsiho and Antsiranana I have relatively low malaria incidence rates and have been selected by the National Malaria Control Programme for pilot elimination strategies.
Elisabeth Gebreegziabher, Andry Raoliarison, Andrinirina Ramananjato, Andriamamonjy Fanomezana, Martin Rafaliarisoa, Sandy Ralisata, Jocelyn Razafindrakoto, Jennifer L. Smith, Jehan Ahmed, Cara Smith Gueye   +9 more
doaj   +1 more source

Prevalence of K13 mutation and Day-3 positive parasitaemia in artemisinin-resistant malaria endemic area of Cambodia: a cross-sectional study

Malaria Journal, 2017
Background The presence of artemisinin-resistant malaria parasites was confirmed in western Cambodia in 2009. In 2013, mutations in the propeller domain of the kelch protein K13 was found to be associated with artemisinin resistance.
Soy Ty Kheang, Siv Sovannaroth, Sovann Ek, Say Chy, Phally Chhun, Sokkieng Mao, Sokomar Nguon, Dy Soley Lek, Didier Menard, Neeraj Kak   +9 more
doaj   +1 more source

Telecom data for efficient malaria interventions [PDF]

arXiv, 2016
Telecom data is rich on mobility information and as such can be used to identify mobility patterns of people in near real time, enabling to build epidemiological models for understanding where epidemics might spread over time. Based on previous research, we have built an operational tool fed with telecom data which shows malaria risk flows in Zambia in
arxiv  

Malaria parasite detection increases during pregnancy in wild chimpanzees [PDF]

, 2014
Background: The diversity of malaria parasites (Plasmodium sp.) infecting chimpanzees (Pan troglodytes) and their close relatedness with those infecting humans is well documented. However, their biology is still largely unexplored and there is a need for
Boesch, Christophe, Calvignac-Spencer, Sébastien, De Nys, Hélène, Dorny, Pierre, Leendertz, Fabian, Mundry, Roger, Wittig, Roman M   +6 more
core   +4 more sources

Do malaria preventive interventions reach the poor? Socioeconomic inequities in expenditure on and use of mosquito control tools in Sudan.

, 2005
OBJECTIVES: To determine levels of socioeconomic inequities in the prevention of malaria, and to examine the implications of the findings for improving the equitable control of malaria in the Sudan.
Malik, El-Fatih, Mnzavaa, Abraham, Mustafa, Sara Hassan, Onwujekwe, Obinna   +3 more
core   +1 more source

Over-diagnosis of malaria is not a lost cause. [PDF]

, 2006
BACKGROUND: Recent studies have highlighted the over-diagnosis of malaria in clinical settings in Africa. This study assessed the impact of a training programme implemented as part of an intervention trial on diagnostic behaviour of clinicians in a rural
Daniel Ch, Jackline Mosha, Paul M Masika, Raymond Urassa, Roly D Gosling, Roly D Gosling, Waziri J Semarundu   +6 more
core   +3 more sources

Estimating Malaria Vaccine Efficacy in the Absence of a Gold Standard Case Definition: Mendelian Factorial Design [PDF]

arXiv, 2019
Accurate estimates of malaria vaccine efficacy require a reliable definition of a malaria case. However, the symptoms of clinical malaria are unspecific, overlapping with other childhood illnesses. Additionally, children in endemic areas tolerate varying levels of parasitemia without symptoms.
arxiv  

Worldwide malaria incidence and cancer mortality are inversely associated [PDF]

, 2018
BACKGROUND: Investigations on the effects of malaria infection on cancer mortality are limited except for the incidence of Burkitt’s lymphoma (BL) in African children.
Liu, P.
core   +1 more source

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria

Malaria Journal, 2018
Over the last 15 years, the majority of malaria drug discovery and development efforts have focused on new molecules and regimens to treat patients with uncomplicated or severe disease.
Fiona Macintyre, Hanu Ramachandruni, Jeremy N. Burrows, René Holm, Anna Thomas, Jörg J. Möhrle, Stephan Duparc, Rob Hooft van Huijsduijnen, Brian Greenwood, Winston E. Gutteridge, Timothy N. C. Wells, Wiweka Kaszubska   +11 more
doaj   +1 more source