Results 131 to 140 of about 747,084 (353)
Malaria, with reference to (1) The danger of imported anopheline insects, (2) An unusual breeding ground [PDF]
L. Bousfield
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A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono+8 more
wiley +1 more source
Advances in analyzing and engineering plant metabolic diversity
Applications in Plant Sciences, EarlyView.
Kira J. Tiedge+3 more
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Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi+7 more
wiley +1 more source
Synthesis of New N,N′‐Diarylureas and Their Theoretical Study as Cannabinoid‐1 Receptor Inhibitors
A series of new pyrazolo‐ and triazolo‐based N,N′‐diarylureas is synthesized following the triphosgene protocol in the last step. Density functional theory calculations and molecular docking provide strong evidence that all new compounds bind strongly to the cannabinoid‐1 (CB‐1) receptor, showing comparable results with the known allosteric CB‐1 ...
Eirini Tsemperlidou+4 more
wiley +1 more source
Costing Artemisinin-based Combination Therapy for Malaria in Tanzania [PDF]
Malaria continues to be a major contributor to the burden of disease in Tanzania, with a prevalence of 33.39 percent nationally. As antimalarial resistance to sulfadoxine-pyrimethamine in Tanzania continues to grow, the government is in the process of ...
Derriennic, Yann, Wolf, Katherine
core
Sickling in Relation to Morbidity from Malaria and Other Diseases [PDF]
A. B. Raper
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