Results 141 to 150 of about 747,084 (353)

Populations Addressed in Vaccines Approved via the European Medicines Agency

Clinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf, Lukas Westphal, Jonathan Kimmelman, Christine E. Hallgreen   +3 more
wiley   +1 more source

Phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula Province, Mozambique

Malaria Journal
Background Seasonal malaria chemoprevention (SMC) is a highly effective intervention for malaria prevention in high burden areas with seasonal transmission, historically implemented in the Sahel.
Kevin Baker, Ivan Alejandro Pulido Tarquino, Pedro Aide, Craig Bonnington, Christian Rassi, Sol Richardson, Chuks Nnaji, Arantxa Roca-Feltrer, Maria Rodrigues, Mercia Sitoe, Sonia Enosse, Caitlin McGugan, Francisco Saute, Gloria Matambisso, Baltazar Candrinho   +14 more
doaj   +1 more source

Community-based Approach to Intermittent Preventive Treatment for Malaria in Pregnancy in Kisumu, Kenya [PDF]

, 2014
Malaria in pregnancy (MiP) is a significant contributor to maternal and newborn morbidity and mortality. In malaria-endemic countries, especially those in tropical areas of Africa where there is intense transmission of Plasmodium falciparum (P ...

core  

Remarks on malaria and acclimatisation [PDF]

, 1893
H. Maktyn Clark
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Advances in Knowledge of the Malaria Parasite [PDF]

, 1950
H. E. Shortt
openalex   +1 more source

Removal of adsorbable organic halides from wastewater: A review of advanced chemical and electrochemical processes

Environmental Progress &Sustainable Energy, EarlyView.
Abstract To overcome the current limitations of conventional technologies for removing adsorbable organic halides (AOX) from wastewater, advanced chemical and electrochemical processes are attracting interest. This work aims to systematically review the latest findings for the removal of AOX compounds from wastewater, discussing the current main gaps ...
Marco Carnevale Miino, Maria Cristina Collivignarelli, Stefano Bellazzi, Alessandro Abbà, Marco Baldi, Alberto Pietro Damiano Baltrocchi, Elena Cristina Rada, Vincenzo Torretta   +7 more
wiley   +1 more source

RTS,S/AS02 and the quest of the Holy Grail [PDF]

, 2002
High-profile programs under the WHO/Roll Back Malaria initiative, in addition to unravelling the human and malaria parasite genomes, have ensured that malaria vaccine research and development are enjoying an unprecedented boom. So far, the development of
Reithinger, R
core  

ON A CONVENIENT TERMINOLOGY FOR THE VARIOUS STAGES OF THE MALARIA PARASITE [PDF]

, 1902
E. Ray Lankester
openalex   +1 more source

Malaria vaccination and rebound malaria [PDF]

The Lancet Infectious Diseases, 2019
Brian Greenwood, Alassane Dicko
openaire   +3 more sources