Results 251 to 260 of about 522,734 (372)

Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings

open access: yesPediatric Discovery, EarlyView.
Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong   +13 more
wiley   +1 more source

A roadmap of priority evidence gaps for the co-implementation of malaria vaccines and perennial malaria chemoprevention. [PDF]

open access: yesMalar J
Grant J   +1 more
europepmc   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

open access: yesNature, 2017
B. Mordmüller   +32 more
semanticscholar   +1 more source

Enhancing Functional Protein Design Using Heuristic Optimization and Deep Learning for Anti‐Inflammatory and Gene Therapy Applications

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein sequence design is a highly challenging task, aimed at discovering new proteins that are more functional and producible under laboratory conditions than their natural counterparts. Deep learning‐based approaches developed to address this problem have achieved significant success.
Ayşenur Soytürk Patat   +1 more
wiley   +1 more source

Comparative transcriptomics reveals different profiles between diflubenzuron‐resistant and ‐susceptible phenotypes of the mosquito Culex pipiens

open access: yesPest Management Science, EarlyView.
Comparative gene expression analysis between susceptible and diflubenzuron‐resistant individuals of the mosquito Culex pipiens revealed transcriptional changes of multiple genes associated with insecticide detoxification and cuticle synthesis. Abstract Background Chitin‐synthesis inhibitors (CSIs) represent a major tool in vector control. The intensive
Mastrantonio Valentina   +7 more
wiley   +1 more source

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