Results 181 to 190 of about 44,517 (310)

Short‐Course Low‐Dose Primaquine for Radical Cure in G6PD‐Normal Patients in the Pre‐Elimination Context of Nepal

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Plasmodium vivax remains a challenge for malaria elimination in Nepal due to its ability to relapse. Radical cure with primaquine is effective but limited by poor adherence to the standard 14‐day low‐dose regimen. In 2022, the WHO recommended administering the same total dose (3.5 mg/kg) over 7 days to improve adherence.
Prakash Ghimire   +18 more
wiley   +1 more source

malERA: An updated research agenda for diagnostics, drugs, vaccines, and vector control in malaria elimination and eradication

open access: yes
Since the turn of the century, a remarkable expansion has been achieved in the range and effectiveness of products and strategies available to prevent, treat, and control malaria, including advances in ...
malERA Refresh Consultative Panel on Tools for Malaria Elimination   +1 more
core  

Altered Pharmacokinetics and Delayed Sputum Conversion in Tuberculosis Patients Co‐Infected With HIV

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background HIV co‐infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first‐line anti‐TB drugs and clinical outcomes in patients with and without HIV co‐infection. Methods In this prospective observational study, 61 adults with sputum‐positive pulmonary TB, either confirmed ...
Aung Pyae Phyo   +14 more
wiley   +1 more source

Malaria elimination practices in China from the perspective of health system and social development. [PDF]

open access: yesInfect Dis Poverty
Song X   +8 more
europepmc   +1 more source

Transfusion‐transmitted malaria in India: A national survey of epidemiology and testing practices

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Malaria still poses a public health burden in India despite ongoing elimination efforts. Blood donor screening for malaria is mandated in India, yet data on transfusion‐transmitted malaria (TTM) are lacking. We sought to evaluate testing practices for malaria, associated rates of positivity in donors and reported ...
Jeremy W. Jacobs   +10 more
wiley   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Local Malaria Elimination [PDF]

open access: yesAmerican Entomologist, 2017
Anton Alexander, Florence V Dunkel
openaire   +1 more source

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