Results 161 to 170 of about 89,833 (263)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Malaria transmission dynamics, vector diversity, and insecticide resistance profiles in two health districts of southern Benin. [PDF]

BMC Infect Dis
Agonhossou R, Akoton R, Koukpo ZC, Ahouandjinou MJ, Zinsou JF, Honkpéhèdji YJ, Adegnika OS, Osse R, Padonou GG, Boussougou-Sambe TS, Mbama Ntabi JD, Lissom A, Nkemngo FN, Ntoumi F, Wondji CS, Borrmann S, Adegnika AA.   +16 more
europepmc   +1 more source

Differential Effect of Ivermectin on Intestinal Helminths in Multimmate Mouse (Mastomys natalensis)

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Mastomys natalensis harbours gastrointestinal helminths of public health and food‐safety importance. This study identified five helminth taxa and assessed faecal egg counts after a single ivermectin dose. Egg counts declined substantially in treated rodents but changed little in controls over eight weeks.
Claus Thomas, Venance Msoffe, Gilbert Mwamengele, Stella Kessy, Emmanuel Hape, Godfrey Katusi, Christopher Sabuni, Isaac Makundi, Herwig Leirs, Robert Machang'u   +9 more
wiley   +1 more source

Behavioral patterns of humans and Anopheles arabiensis reveal outdoor malaria transmission risk at Pemba Island, Zanzibar. [PDF]

Malar J
Ali AO, Khatib BO, Ali KF, Massoud FA, Khatib TS, Rashid MK, Gowelo S, Shija SJ, Omar KA, Kombo MM, Joseph JJ, Govella NJ, Lobo NF.   +12 more
europepmc   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

Acta Paediatrica, Volume 115, Issue 11, Page 2498-2504, November 2026.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

Climatic and governance determinants of malaria transmission in Rivers State, Nigeria. [PDF]

Sci Rep
Egbom SE, Nduka FO, Nzeako SO, Nwafor GO, Bartholomew DC, Nwaigwe CC, Iwu HC, Ogbonna CJ, Nwokike CI, Opara MC, Ezenwaka CO, Anyanwu EO, Nwachukwu JI.   +12 more
europepmc   +1 more source

Trained Immunity in Childhood Vaccination

Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Impact of the COVID-19 pandemic on malaria transmission in the state of Pará, Brazil. [PDF]

Malar J
de Sá CAF, Sardinha DM, de Paula Souza E Guimarães RJ, Vallinoto ACR, Dos Santos EJM, Viana GMR, do Socorro Souza Chaves T.   +6 more
europepmc   +1 more source

Reducing Malaria Transmission in Africa

PLoS Medicine, 2005
openaire   +3 more sources

Community Stakeholder Perspectives on Children With Cerebral Palsy and Their Caregivers: A Qualitative Study From Rural Malawi

Child: Care, Health and Development, Volume 52, Issue 6, November 2026.
ABSTRACT Background Cerebral palsy (CP) disproportionately affects children in low‐ and middle‐income countries, where stigma and discrimination lead to marginalization and reduced participation. To design culturally appropriate community‐based health promotion strategies that can address these challenges, the role of community stakeholders is crucial,
Bente van der Meijden, Victoria von Salmuth, Alpheus Njewa, Alinafe Chisulanda Kusate, Ria Reis, Wieger Voskuijl   +5 more
wiley   +1 more source