Results 31 to 40 of about 89,833 (263)

Antibody-Dependent Respiratory Burst against Plasmodium falciparum Merozoites in Individuals Living in an Area with Declining Malaria Transmission

Vaccines
Malaria transmission intensity affects the development of naturally acquired immunity to malaria. An absolute correlate measure of protection against malaria is lacking.
Doreen D. Mutemi, James Tuju, Rodney Ogwang, Lydia Nyamako, Kennedy M. Wambui, Ivette R. Cruz, Pär Villner, Victor Yman, Samson M. Kinyanjui, Ingegerd Rooth, Billy Ngasala, Anna Färnert, Faith H. A. Osier   +12 more
doaj   +1 more source

Seasonally dependent relationships between indicators of malaria transmission and disease provided by mathematical model simulations. [PDF]

PLoS Computational Biology, 2014
Evaluating the effectiveness of malaria control interventions on the basis of their impact on transmission as well as impact on morbidity and mortality is becoming increasingly important as countries consider pre-elimination and elimination as well as ...
Erin M Stuckey, Thomas Smith, Nakul Chitnis   +2 more
doaj   +1 more source

Larviciding to prevent malaria transmission

Cochrane Database of Systematic Reviews, 2019
Larviciding refers to the regular application of chemical or microbial insecticides to water bodies or water containers to kill the aquatic immature forms of the mosquito (the larvae and pupae).To summarize research evidence evaluating whether larviciding with chemical or microbial insecticides prevents malaria transmission.We searched the Cochrane ...
Choi, Leslie, Majambere, Silas, Wilson, Anne   +2 more
openaire   +3 more sources

Malaria on the Move: Human Population Movement and Malaria Transmission [PDF]

Emerging Infectious Diseases, 2000
Reports of malaria are increasing in many countries and in areas thought free of the disease. One of the factors contributing to the reemergence of malaria is human migration. People move for a number of reasons, including environmental deterioration, economic necessity, conflicts, and natural disasters. These factors are most likely to affect the poor,
Martens, P., Hall, L.
openaire   +3 more sources

Geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in Ratanakiri, Cambodia

Malaria Journal, 2016
Background Malaria transmission is highly heterogeneous, especially in low endemic countries, such as Cambodia. This results in geographical clusters of residual transmission in the dry, low transmission season, which can fuel the transmission to wider ...
Karen Kerkhof, Vincent Sluydts, Somony Heng, Saorin Kim, Myrthe Pareyn, Laura Willen, Lydie Canier, Siv Sovannaroth, Didier Ménard, Tho Sochantha, Marc Coosemans, Lies Durnez   +11 more
doaj   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

Exploring the longitudinal expression dynamics of midguts in adult female Amblyomma americanum ticks

BMC Genomics
Background Female ticks remain attached to their host for multiple days to complete a blood meal. This prolonged feeding period is accompanied by a significant increase in the tick’s size and body weight, paralleled by noteworthy changes to the tick ...
Stephen Lu, Lucas C. de Sousa-Paula, Jose M. C. Ribeiro, Lucas Tirloni   +3 more
doaj   +1 more source

Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity

Malaria Journal, 2009
Background The understanding of the epidemiology of severe malaria in African children remains incomplete across the spectrum of Plasmodium falciparum transmission intensities through which communities might expect to transition, as intervention coverage
Idro Richard, Reyburn Hugh, Al-Taiar Abdullah, Okiro Emelda A, Berkley James A, Snow Robert W   +5 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Assessing the effects of global warming and local social and economic conditions on the malaria transmission

Revista de Saúde Pública, 2000
OBJECTIVE: To show how a mathematical model can be used to describe and to understand the malaria transmission. METHODS: The effects on malaria transmission due to the impact of the global temperature changes and prevailing social and economic conditions
Hyun M Yang, Marcelo U Ferreira
doaj   +3 more sources