Results 71 to 80 of about 89,833 (263)

Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis.

PLoS ONE, 2010
BackgroundThere is evidence that the age-pattern of Plasmodium falciparum malaria varies with transmission intensity. A better understanding of how this varies with the severity of outcome and across a range of transmission settings could enable locally ...
Ilona Carneiro, Arantxa Roca-Feltrer, Jamie T Griffin, Lucy Smith, Marcel Tanner, Joanna Armstrong Schellenberg, Brian Greenwood, David Schellenberg   +7 more
doaj   +1 more source

Review of phytochemical and antioxidant properties of Ethiopian medicinal plants

JSFA reports, EarlyView.
Abstract Ethiopia possesses a rich ethnobotanical heritage and diverse medicinal flora that play an important role in traditional healthcare. Many Ethiopian medicinal plants contain bioactive phytochemicals with potential antioxidant properties. This capital of indigenous knowledge has contributed to the documentation of different medicinal plants that
Endalamaw Yihune, Amare Bitew Mekonnen, Getahun Yemata   +2 more
wiley   +1 more source

Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa

BMC Medicine, 2017
Background Malaria transmission intensity is heterogeneous, complicating the implementation of malaria control interventions. We provide a description of the spatial micro-epidemiology of symptomatic malaria and asymptomatic parasitaemia in multiple ...
Polycarp Mogeni, Irene Omedo, Christopher Nyundo, Alice Kamau, Abdisalan Noor, Philip Bejon, on behalf of The Hotspot Group Authors   +6 more
doaj   +1 more source

Malaria Transmission and Prospects for Malaria Eradication: The Role of the Environment [PDF]

Cold Spring Harbor Perspectives in Medicine, 2017
Environmental factors affect the transmission intensity, seasonality, and geographical distribution of malaria, and together with the vector, the human, and the parasite compose the malaria system. Strategies that alter the environment are among the oldest interventions for malaria control, but currently are not the most prominent despite historical ...
openaire   +2 more sources

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni, Niccolò Capurro, Alessandro Svizzero, Valeria Brazzelli   +3 more
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Climate change and malaria: an old enemy of Africa is back

BMC Public Health
Background Malaria is one of the deadliest transmissible diseases in Sub-Saharan Africa. The control of malaria is hindered by socio-economic and environmental factors and its growth is also associated with climate change, particularly temperature ...
Walter Leal Filho, Gouvidé Jean Gbaguidi, Roberto Ariel Abeldaño Zuñiga, Umar Ibrahim   +3 more
doaj   +1 more source

Human–wildlife coexistence and social context: Evidence from farmer communities in southern Sri Lanka

People and Nature, EarlyView.
Abstract Studies on human–wildlife interactions (HWI) often focus on conflict mitigation studies, thus overlooking underlying factors that influence community decisions to coexist with wildlife. To address this knowledge gap, we collected empirical evidence of how community interactions with wildlife are shaped by their social contexts.
Anuradhi Dulangi Jayasinghe, Georgette Leah Burns, Johanna Nalau, Duan Biggs   +3 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source