Results 11 to 20 of about 76,469 (250)

Identification of major malate export systems in an engineered malate producing Escherichia coli aided by substrate similarity search

Optimization of export mechanisms for valuable extracellular products is important for the development of efficient microbial production processes. Identification of the relevant export mechanism is the prerequisite step for product export optimization ...
Rodriguez-Sanchez, Yesenia, Kurgan, Logan, Taylor, Eric, Schneider, Aidan, Carbonell, Pablo, Wang, Xuan, Kurgan, Gavin   +6 more
core   +11 more sources

Malolactic Fermentation:Electrogenic Malate Uptake and Malate/Lactate Antiport Generate Metabolic Energy [PDF]

, 1991
The mechanism of metabolic energy production by malolactic fermentation in Lactococcus lactis has been investigated. In the presence of L-malate, a proton motive force composed of a membrane potential and pH gradient is generated which has about the same
Konings, Wil N., Ubbink, Trees, Molenaar, Douwe, Smid, Eddy J., Renault, Pierre P., Poolman, Bert, Abee, Tjakko   +6 more
core   +6 more sources

Malic Acid Production by Saccharomyces cerevisiae: Engineering of Pyruvate Carboxylation, Oxaloacetate Reduction, and Malate Export [PDF]

, 2008
Malic acid is a potential biomass-derivable "building block" for chemical synthesis. Since wild-type Saccharomyces cerevisiae strains produce only low levels of malate, metabolic engineering is required to achieve efficient malate production with this ...
Van Maris, A.J.A. (author), Dijkema, C., Van Winden, W.A. (author), Winden, W.A., van, Dijkema, C. (author), Zelle, R.M. (author), Van Maris, A.J.A., Van Winden, W.A., De Hulster, E., Geertman, J.M., Pronk, J.T. (author), Hulster, E., de, Geertman, J.M.A., Winkler, A.A. (author), Van Dijken, J.P., Pronk, J.T., Winkler, A.A., De Hulster, E. (author), De Waard, P. (author), Geertman, J.M. (author), Waard, P., de, Zelle, R.M., De Waard, P., Van Dijken, J.P. (author)   +23 more
core   +2 more sources

Plasma N-Terminal Pro-Brain Natriuretic Peptide as Prognostic Marker in Fatal Cardial Decompensation with Sunitinib Malate Therapy [PDF]

, 2010
A 74-year-old man with metastatic renal cell carcinoma and a history of cardiac failure was treated with sunitinib malate. MUGA echocardiography could not detect a relevant change in the ejection fraction although the clinical situation of the patient ...
Stief, Christian G., Stadler, Thomas, Zilinberg, Katja, Haseke, Nicolas, Staehler, Michael   +4 more
core   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Determining Commercial Parking Vacancies Employing Multiple WiFiRSSI Fingerprinting Method

Journal of Sensor and Actuator Networks, 2023
In this study, we implemented a parking occupancy/vacancy detection system (POVD) in a scaled-down model of a parking system for commercial centers by employing multiple WiFi access points.
Elmer Magsino, Juan Miguel Carlo Barrameda, Andrei Puno, Spencer Ong, Cyrill Siapco, Jolo Vibal   +5 more
doaj   +1 more source

Modeling the Hydrologic Performance and Cost-Effectiveness of LID in a Residential Park Area Using a Decentralized Design Approach

Hydrology, 2022
Low Impact Development (LID) is one of the current research interests toward green infrastructures and urban flood control that have the capability to return developed watersheds to pre-development hydrological conditions, bringing numerous water ...
Sergi Garbanzos, Marla Maniquiz-Redillas
doaj   +1 more source

‐malate

, 2020
Promiscuous activities of enzymes may serve as starting points for the evolution of new functions. However, most experimental examples of promiscuity affording an observable phenotype necessitate the artificial overexpression of the target enzyme.
Soumillion, Patrice, Gargiulo, Serena, Serena Gargiulo, Patrice Soumillion, Mohammad Shahneawz Khan, Khan, Mohammad Shahneawz   +5 more
core   +1 more source

MdWRKY126 modulates malate accumulation in apple fruit by regulating cytosolic malate dehydrogenase (MdMDH5)

, 2022
The content of organic acids greatly influences the taste and storage life of fleshy fruit. Our current understanding of the molecular mechanism of organic acid accumulation in apple (Malus domestica) fruit focuses on the aluminum-activated malate ...
Ma, Fengwang, Chen, Xingyu, Ruan, Yong Ling, Yuan, Yangyang, Li, Mingjun, Ma, Baiquan, Ruan, Yong-Ling, Zhang, Lihua, Wang, Changzhi   +8 more
core   +1 more source