Results 81 to 90 of about 193,136 (209)

Malate dehydrogenase activity in human seminal plasma and spermatozoa homogenates

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Purpose: Malate Dehydrogenase is an important enzyme of the Krebs cycle, most cells require this enzyme for their metabolic activity. We evaluated the Malate Dehydrogenase (NAD/NADP) activity in human seminal plasma and sperm homogenates in ...
Hulya Leventerler, Safiye Taga, Ibrahim Ferhat Urunsak, Ismail Atilla Aridogan, Suna Solmaz, Mehmet Turan Cetin, Nurten Dikmen   +6 more
doaj  

Engineering of Escherichia coli for Krebs cycle-dependent production of malic acid

Microbial Cell Factories, 2018
Background Malate is a C4-dicarboxylic acid widely used as an acidulant in the food and beverage industry. Rational engineering has been performed in the past for the development of microbial strains capable of efficient production of this metabolite ...
Debora Trichez, Clément Auriol, Audrey Baylac, Romain Irague, Clémentine Dressaire, Marc Carnicer-Heras, Stéphanie Heux, Jean Marie François, Thomas Walther   +8 more
doaj   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Effect of Caffeine on the Expression Pattern of Water-Soluble Proteins in Rice () Seedlings

Natural Product Communications, 2015
It has been suggested that caffeine acts as an allelochemical which influences the germination and growth of plants. The effect of caffeine on the expression profiles of proteins was investigated in shoot-root axes of rice (Oryza sativa) seedlings.
Wei-Wei Deng, Hamako Sasamoto, Hiroshi Ashihara   +2 more
doaj   +1 more source

An experimental point of view on hydration/solvation in halophilic proteins

Frontiers in Microbiology, 2014
Protein-solvent interactions govern the behaviour of proteins isolated from extreme halophiles. In this work, we compared the solvent envelopes of two orthologous tetrameric malate dehydrogenases from halophilic and non-halophilic bacteria.
Romain eTalon, Romain eTalon, Romain eTalon, Nicolas eCoquelle, Nicolas eCoquelle, Nicolas eCoquelle, Dominique eMadern, Dominique eMadern, Dominique eMadern, Eric eGirard, Eric eGirard, Eric eGirard   +11 more
doaj   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

Isoenzymes of Malate Dehydrogenase in Saccharomyces cerevisiae

, 1968
Extracts from yeast cells grown under different conditions and from mitochondria were subjected to agar gel electrophoresis. Three bands showing malate dehydrogenase activity were found in extracts from aerobic derepressed cells (c-MDH I, c-MDH II, and m-
Atzpodien, W., Gancedo, Juana M., Duntze, W., Holzer, H.   +3 more
core   +1 more source

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

The Journal of Pathology, EarlyView.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti, Martina Brigida Romanello, Luca Agnelli, Matteo Orlandi, Luca Bertoli, Sara Picinoli, Irene Pezzali, Giulio Eugenio Mandelli, Daniela Medicina, Giovanni Ribaudo, Adele Busico, Elena Conca, Vilma Pellegrini, Piera Balzarini, Daniele Gallucci, Anna Di Matteo, Davide Lombardi, Claudia Ghigna, Giancarlo Pruneri, Alessandra Gianoncelli, Marzia Rossato, William Vermi   +21 more
wiley   +1 more source

Role of NAD+-Dependent Malate Dehydrogenase in the Metabolism of Methylomicrobium alcaliphilum 20Z and Methylosinus trichosporium OB3b

Microorganisms, 2015
We have expressed the l-malate dehydrogenase (MDH) genes from aerobic methanotrophs Methylomicrobium alcaliphilum 20Z and Methylosinus trichosporium OB3b as his-tagged proteins in Escherichia coli.
Olga N. Rozova, Valentina N. Khmelenina, Ksenia A. Bocharova, Ildar I. Mustakhimov, Yuri A. Trotsenko   +4 more
doaj   +1 more source