This study investigated the effect of L‐citrulline supplementation on BP under cold exposure and found that it significantly reduced both SBP and DBP, thereby alleviating cold‐induced hypertension, thus providing a scientific basis for cardiovascular protection. Future studies should further investigate its optimal dosage.
Ping Luo +3 more
wiley +1 more source
Understanding the Role of pH Regulation and Neutralizing Agents in Organic Acid Production and Growth of Aspergillus oryzae. [PDF]
Hartmann L +4 more
europepmc +1 more source
Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco +16 more
wiley +1 more source
Sex dimorphism and substrate dependency of liver mitochondrial bioenergetics and H<sub>2</sub>O<sub>2</sub> production. [PDF]
Dave DD +6 more
europepmc +1 more source
Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham +4 more
wiley +1 more source
Effects of Acute Citrulline Malate Supplementation on CrossFit® Exercise Performance: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study. [PDF]
Devrim-Lanpir A +13 more
europepmc +1 more source
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression. [PDF]
Zhao K +10 more
europepmc +1 more source
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov +16 more
wiley +1 more source
RIPK3 promotes ASIC1a-mediated fibroblast-like synoviocyte migration and invasion via malate shuttle-driven mitochondrial respiration in rheumatoid arthritis. [PDF]
Hu W +13 more
europepmc +1 more source

